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Cough in Reduced True Vocal Fold Mobility

NCT02407301 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2016-05-13

No results posted yet for this study

Summary

This project is a first attempt to assess cough airflow dynamics and true vocal fold (TVF) adduction and abduction angles during voluntary cough to examine the effects of changes in glottal closure due to reduced mobility of one true vocal fold. The hypothesis of this study is that the incomplete glottal closure due to reduced vocal fold mobility will result in changes in true vocal fold adductory and abductory angles during cough and will result in changes to voluntary cough airflow parameters. This study results will contribute to the existing knowledge of the laryngeal contribution to cough airflow dynamics.

Conditions

  • Unilateral Vocal Cord Paresis
  • Unilateral Vocal Cord Paralysis

Interventions

OTHER

cough airflow measure

Participants will produce multiple voluntary coughs for cough airflow assessment.

OTHER

vocal tasks

The assessment of glottal closure will be performed during phonation tasks.

OTHER

true vocal fold movement

The true vocal fold (TVF) movement in cough will be observed and recorded during cough production.

OTHER

spirometry test

The lung function test will require the participant to perform deep inhalations and forceful exhalations into the flow head of the spirometer during spirometry test.

OTHER

maximum expiratory pressure (MEP)

The assessment of maximum expiratory pressure will require forceful exhalations into a mouthpiece of a manometer during maximum expiratory pressure (MEP) assessment.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Karen W Hegland, Ph.D. · University of Florida

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-30
Primary Completion
2016-02-29
Completion
2016-02-29

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02407301 on ClinicalTrials.gov