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CRIC-Visceral Adiposity and Physical Fitness in Chronic Kidney Disease

NCT02405650 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 453

Last updated 2019-07-22

No results posted yet for this study

Summary

Obesity and chronic kidney disease (CKD) are major public health problems. In contrary to observations in general population, higher body mass index in those with pre-existing CKD is associated with lower mortality. Chronic Renal Insufficiency Cohort (CRIC) is an ongoing observational study to examine the consequences of CKD with a particular focus on cardiovascular illness like myocardial infarction (heart attack) and stroke. Among CRIC study participants, the investigators propose to obtain visceral and subcutaneous adiposity and physical fitness measures and study its associations with patient-centered outcomes. This study will help the investigators understand the independent and combined effects of visceral adiposity and physical fitness on cardiovascular disease, renal disease progression and death among those with CKD. Further, it will identify mechanisms that could be targeted to reduce the detrimental effects of visceral adiposity in those with kidney disease.

Conditions

  • Renal Insufficiency, Chronic
  • Obesity

Sponsors & Collaborators

  • University of Pennsylvania

    collaborator OTHER

  • Case Western Reserve University

    collaborator OTHER

  • University of Michigan

    collaborator OTHER

  • University of Illinois at Chicago

    collaborator OTHER

  • University of Maryland

    collaborator OTHER

  • MetroHealth Medical Center

    collaborator OTHER

  • The Cleveland Clinic

    collaborator OTHER

  • Johns Hopkins University

    collaborator OTHER

  • Baylor College of Medicine

    lead OTHER

Principal Investigators

  • Sankar Navaneethan, M.D. · Baylor College of Medicine

Eligibility

Min Age
21 Years
Max Age
79 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-04-30
Primary Completion
2018-03-31
Completion
2018-03-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02405650 on ClinicalTrials.gov