Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer
NCT02394548 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27
Last updated 2021-12-09
Summary
This research study is examining the benefit of a novel radiation planning approach on the likelihood of developing severe esophagitis (irritation and inflammation of the esophagus) during the course of radiation therapy with concurrent chemotherapy which is associated with very painful and difficult swallowing.
Conditions
- Non-small Cell Lung Carcinoma
- Small Cell Lung Carcinoma
Interventions
- RADIATION
-
Contralateral Esophageal Sparing Technique (CEST)
Determine whether CEST decreases rate of severe acute esophagitis
Sponsors & Collaborators
-
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Henning Willers, MD · Massachusetts General Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-06-30
- Primary Completion
- 2019-02-28
- Completion
- 2021-03-31
Countries
- United States
Study Locations
More Related Trials
-
Phase I Study of Accelerated Hypofractionated Image-Guided Radiation Therapy
NCT03623334 ·Status: COMPLETED ·Phase: NA
-
An Evaluation of Dose-escalation for Intrathoracic Tumours
NCT06794125 ·Status: RECRUITING ·Phase: NA
-
Phase 1/2 Study to Determine Optimal Dose for Treating Bone Metastases Using Novel STAT-RT Workflow
NCT02145286 ·Status: UNKNOWN ·Phase: NA
-
Prospective Study on Factors Predicting Chemo-Radiotherapy Induced Pulmonary and Esophageal Injury
NCT00631839 ·Status: UNKNOWN
-
Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery
NCT00551369 ·Status: COMPLETED ·Phase: PHASE2
-
Surgery With or Without Internal Radiation Therapy Compared With Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Stage I Non-Small Cell Lung Cancer
NCT01336894 ·Status: TERMINATED ·Phase: PHASE3
-
Investigation of Contralateral Arytenoid Sparing IMRT for T1a & T2a Larynx Cancer & Analysis of Post-treatment Laryngeal Function
NCT02633540 ·Status: TERMINATED ·Phase: PHASE2
-
Ablative SBRT in Elderly BC Patients
NCT06523894 ·Status: RECRUITING ·Phase: NA
-
Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer
NCT00750269 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Stereotactic Ablative Body Radiotherapy (SABR) for Oligometastases
NCT02933242 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial
NCT01512589 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
MR-informed Stereotactic Radiotherapy for Treatment of Ultracentral Lung Tumours Utilising a Dedicated MR-simulator for Daily Adaptation Followed by CBCT-guided Treatment Delivery
NCT06815289 ·Status: RECRUITING ·Phase: NA
-
Functional Imaging in Lung SBRT
NCT03121300 ·Status: COMPLETED
-
Phase II Study of Whole or Partial Parotid Sparing Intensity Modulated Radiotherapy in Patients With Head and Neck Cancers
NCT02068313 ·Status: UNKNOWN
-
Stereotactic Body Radiation Therapy in Treating Patients With Inoperable Stage I or Stage II Non-Small Cell Lung Cancer
NCT00087438 ·Status: COMPLETED ·Phase: PHASE2
-
Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy
NCT01223248 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Combining ICI With SBRT or HypoFrx-RT for ES NSCLC
NCT05451173 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
Stereotactic Radiotherapy (SBRT) of Lung Metastasis
NCT01803542 ·Status: RECRUITING ·Phase: PHASE2
-
TOMO Versus IMRT in Nasopharyngeal Carcinoma Patients
NCT03588403 ·Status: UNKNOWN
-
Randomized Study of Stereotactic Body Radiotherapy vs. Conventional Radiation for Spine Metastasis
NCT01525745 ·Status: TERMINATED ·Phase: PHASE2
-
Phase I/II Study of Fractionated Stereotactic Radiotherapy for Early Stage Non-Small Cell Lung Cancer
NCT00888823 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer
NCT03706027 ·Status: RECRUITING ·Phase: NA
-
Moderate Hypofractionated Radiotherapy for Lung Cancer
NCT03833193 ·Status: UNKNOWN ·Phase: NA
-
Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
NCT00471835 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
A Phase I Evaluating Integration of HypofractionatedStudy Renal Ablative Radiotherapy
NCT02264548 ·Status: COMPLETED ·Phase: PHASE1