European Comparative Effectiveness Research on Internet-based Depression Treatment in Poland

Summary

Effective, accessible, and affordable depression treatment is of high importance considering the large individual and economic burden of depression. There is ample support for the effectiveness of Internet-based Cognitive Behavioral Therapy (CBT) for depression which is considered a promising alternative to routine depression treatment strategies. Most evidence comes from randomized controlled trials, however, and not from research in routine practice.

The European Comparative Effectiveness Research on Internet-based Depression Treatment (E-COMPARED) in Poland aims to compare the clinical and cost-effectiveness of blended CBT for adults with major depressive disorder (MDD) with treatment as usual (TAU). The trial will be conducted in routine mental health care in Poland, and is a part of the bigger project funded by European Commission (Grant Agreement No: 603098). In this randomized controlled trial, a total of 150 patients with MDD will be assigned to one of two conditions: 1) blended CBT, 2) TAU. Respondents in both conditions will be followed until 12 months after baseline (measures will be taken at baseline, 3 months, 6 months and 12 months).

Conditions

• Depression

Interventions

BEHAVIORAL

Blended Cognitive Behavioural Therapy (CBT)

BEHAVIORAL

Treatment as usual

Sponsors & Collaborators

• VU University of Amsterdam

  collaborator OTHER

• Linkoeping University

  collaborator OTHER_GOV

• University of Erlangen-Nürnberg

  collaborator OTHER

• London School of Hygiene and Tropical Medicine

  collaborator OTHER

• GGZ inGeest

  collaborator OTHER

• Universitat Jaume I

  collaborator OTHER

• Leuphana Universität Lünenberg

  collaborator UNKNOWN

• University of Limerick

  collaborator OTHER

• University of Bern

  collaborator OTHER

• University of Valencia

  collaborator OTHER

• Inesc Porto

  collaborator UNKNOWN

• Institut National de la Santé Et de la Recherche Médicale, France

  collaborator OTHER_GOV

• European Commission

  collaborator OTHER

• Ministry of Science and Higher Education, Poland

  collaborator OTHER_GOV

• University of Social Sciences and Humanities, Warsaw

  lead OTHER

Principal Investigators

• Roman Cieslak, PhD · University of Social Sciences and Humanities

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-06-30

Primary Completion

2018-06-30

Completion

2018-06-30

Countries

• Poland

Study Locations