HIV/AIDS Orphaned and Vulnerable Children Public Health Evaluation
NCT02386878 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2302
Last updated 2017-03-13
Summary
The PHE study is a two-year longitudinal study evaluating two interventions for reducing depression and HIV risk behaviors among highly vulnerable adolescents in the Eastern Cape of South Africa. Research suggests that children affected by AIDS are at heightened risk of HIV infection relative to their peers; however, evidence on how best to address HIV prevention and psychological health among this population is lacking. This study examines the efficacy of both a psychological and behavioral intervention, alone and in combination, on related outcomes among vulnerable youth age 14-17. A mixed methods approach is applied, including a community-randomized controlled trial with a factorial design, a cost-effectiveness analysis, and a qualitative component. At baseline data collection in January 2012, more than 1000 adolescents and their caregivers were interviewed; these participants were invited to take part in two more survey rounds designed to examine both the immediate and long term effects of the interventions. Support for this research was provided by USAID under Grant No. GHH-I-00-007-00069-00.
Conditions
- Adolescent Behavior
- Risk Reduction Behavior
- Stress, Psychological
Interventions
- BEHAVIORAL
-
Interpersonal Psychotherapy for Groups (IPTG)
Interpersonal psychotherapy is a theory- and evidence-based treatment approach for depression developed by clinicians. World Vision has helped to pioneer the use of this model in sub-Saharan Africa including adapting the model for use with OVC within South Africa. Sessions are designed to provide participants with opportunities to learn and practice interpersonal skills for solving problems that bring about depression, and to facilitate the provision of emotional support between members of the group. Groups are implemented by a trained adult facilitator from the community who helps participants to identify people who are important in their lives, understand links between their psychological state and current problems, and practice new ways of problem-solving.
- BEHAVIORAL
-
Vhutshilo 2
The Vhutshilo 2 model was developed in 2008 by the Centre for the Support of Peer Education (CSPE), a branch of the South African non-profit organization Health and Education Training and Technical Assistance Services. The Vhutshilo program was designed specifically for adolescent OVC in South Africa, and attends to risk factors and pathways considered particularly relevant for this population. Topics include finding and giving emotional support; dealing with grief and loss; alcohol and substance abuse; crime and sexual violence; HIV/AIDS; healthy and safe sexual relationships; and transactional sex. In addition to its knowledge component, the program places heavy emphasis on building relevant skills and efficacy.
Sponsors & Collaborators
-
United States Agency for International Development (USAID)
collaborator FED -
Tulane University School of Social Work
lead OTHER
Principal Investigators
-
Tonya R Thurman, MPH PhD · Tulane University School of Social Work
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- FACTORIAL
Eligibility
- Min Age
- 14 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-01-31
- Primary Completion
- 2014-01-31
- Completion
- 2014-01-31
More Related Trials
-
Integrated Prevention of HIV Risk and Intimate Partner Violence Among Adolescents in South Africa
NCT03179982 ·Status: COMPLETED ·Phase: NA
-
Brief HIV Prevention Counseling for STI Patients in South Africa
NCT01242501 ·Status: COMPLETED ·Phase: NA
-
MISC-CBO in Children Affected by HIV/AIDS
NCT04359043 ·Status: COMPLETED ·Phase: NA
-
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
NCT05624931 ·Status: RECRUITING ·Phase: NA
-
Improving the Health of South African Women With Traumatic Stress in HIV Care (C0147)
NCT02223390 ·Status: COMPLETED ·Phase: NA
-
Intervention Development for Syndemics Among PWH in SA
NCT06152003 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Therapeutic Schools: Affect Management and HIV Prevention
NCT00500487 ·Status: COMPLETED ·Phase: PHASE1
-
Women-Focused HIV Prevention in the Western Cape
NCT00729391 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Systems Analysis and Improvement Approach to Improve Integration of HIV Prevention and Treatment Services
NCT05404958 ·Status: RECRUITING ·Phase: NA
-
A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women
NCT04758390 ·Status: COMPLETED ·Phase: NA
-
School Support as Structural HIV Prevention for Adolescent Orphans in Kenya
NCT01501864 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of a Pre-adolescent Inter-generational Intervention to Address HIV and Obesity
NCT04307966 ·Status: COMPLETED
-
HIV Prevention for PLHIV: Evaluation of an Intervention Toolkit for HIV Care & Treatment Settings
NCT01256463 ·Status: COMPLETED ·Phase: NA
-
Traditional Healer-initiated HIV Counseling and Testing in South Africa
NCT05079347 ·Status: COMPLETED ·Phase: NA
-
Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents
NCT00640653 ·Status: COMPLETED ·Phase: NA
-
Pediatric HIV Disclosure Intervention
NCT01773642 ·Status: COMPLETED ·Phase: NA
-
Home Link: Post Hospital Care to Reduce HIV Mortality in South Africa
NCT04436289 ·Status: COMPLETED ·Phase: NA
-
Peer Support to Mitigate the Impact of Stigma in Young HIV+ Pregnant & Postpartum Women
NCT04036851 ·Status: COMPLETED ·Phase: NA
-
Male Partner Involvement in the Prevention of MTCT of HIV
NCT00405990 ·Status: COMPLETED ·Phase: PHASE4
-
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
NCT02432352 ·Status: COMPLETED ·Phase: PHASE1
-
Reducing HIV in Adolescents
NCT01187979 ·Status: COMPLETED ·Phase: PHASE2
-
Experimental Analysis of HIV Risk Assessment Reactivity in South African Clinics
NCT01580657 ·Status: COMPLETED ·Phase: NA
-
Assessing the Impact of an Intervention to Prevent Intimate Partner Violence and HIV in Uganda
NCT02050763 ·Status: COMPLETED ·Phase: NA
-
Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa
NCT04205721 ·Status: COMPLETED ·Phase: NA
-
Safer Conception for Women - Understanding Use of Periconception PrEP
NCT03194308 ·Status: COMPLETED ·Phase: PHASE4