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Glucose Metabolism in Subjects With Aldosterone-Producing Adenomas

NCT02362308 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2021-05-04

No results posted yet for this study

Summary

This observational study tests the hypothesis that endogenous aldosterone impairs insulin secretion and insulin sensitivity in subjects with primary aldosteronism.

Conditions

  • Primary Aldosteronism

Interventions

OTHER

Adrenalectomy

Adrenalectomy for treatment of primary aldosteronism, according to standard of care

DRUG

mineralocorticoid receptor antagonist

Subjects will be treated with a mineralocorticoid receptor antagonist according to standard of care

Sponsors & Collaborators

  • Brigham and Women's Hospital

    collaborator OTHER

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • Vanderbilt University

    lead OTHER

Principal Investigators

  • James M Luther, MD · Vanderbilt University Medical Center

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2020-01-31
Completion
2020-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02362308 on ClinicalTrials.gov