Evaluation of Diffusion Weighted Imaging -MRI in Patients With Resectable Liver Metastases From Colorectal Cancer
NCT02355353 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 31
Last updated 2015-02-04
Summary
The primary objective of this study is to correlate the percentage change in apparent diffusion coefficient (ADC) between baseline and early therapy (at day 14) with tumor regression grade (TRG) measured in the surgical resection specimen.
Conditions
- Liver Metastases
- Colorectal Cancer
Interventions
- OTHER
-
Experimental: imaging arm
DWI-MRI scans at baseline, at 14 days after first administration of chemotherapy and after up to 6 cycles of chemotherapy
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Sigrid Stroobants · Universitair Ziekenhuis Brussel
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-02-28
- Primary Completion
- 2016-09-30
- Completion
- 2017-02-28
More Related Trials
-
Perfusion and Diffusion Magnetic Resonance Imaging, and Phosphorylation of Circulation Endothelial Cells to Determine Anti-anogenic Effect of Chemotherapeutic Regimens in Colorectal Liver Metastasis Patients
NCT01318239 ·Status: COMPLETED ·Phase: NA
-
Study of Immune Response and Liver Damage Induced by Chemotherapy for Liver Metastases of Colorectal Cancer
NCT01673607 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparison of Primovist-enhanced MRI, Diffusion Weighted MRI and Multidetector CT of Colorectal Liver Metastases
NCT01255007 ·Status: COMPLETED ·Phase: NA
-
Impact of Positron Emission Tomography Imaging Prior to Liver Resection for Colorectal Adenocarcinoma Metastases
NCT00265356 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment Response Evaluation in Patients With Non-resectable Colorectal Liver Metastases A Feasibility Study
NCT03444194 ·Status: UNKNOWN ·Phase: NA
-
Circulating Tumor Cells in mCRC for Liver Resection
NCT03295591 ·Status: UNKNOWN
-
Exploratory Study in Achievement of Improved Survival by Molecular Targeted Chemotherapy and Liver Resection for Not Optimally Resectable Colorectal Liver Metastases
NCT01834014 ·Status: COMPLETED ·Phase: NA
-
Comparison of Triphasic CT, PET and MR Tumour With Pathological Findings in Colorectal Cancer Liver Metastases
NCT00242086 ·Status: COMPLETED ·Phase: NA
-
Multi-modality Imaging in the Prediction of Response to Systemic Treatment in Colorectal Cancer
NCT01292681 ·Status: UNKNOWN ·Phase: NA
-
An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
NCT04796818 ·Status: RECRUITING ·Phase: NA
-
Evaluation of Metabolic Activity of Liver Metastases by FDG-PET Scanning
NCT00184782 ·Status: UNKNOWN ·Phase: NA
-
Utility of PET In the Pre-Operative Assessment of Patients With Hepatic Colorectal Metastases
NCT00588549 ·Status: COMPLETED
-
Impact of Preoperative Chemotherapy on Complications and Regeneration After Resection of Colorectal Liver Metastases
NCT00779272 ·Status: COMPLETED
-
Dynamic ctDNA Detection for Colorectal Cancer Liver Metastases
NCT06404593 ·Status: COMPLETED
-
Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
NCT05248581 ·Status: RECRUITING
-
Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases
NCT03488953 ·Status: RECRUITING ·Phase: NA
-
Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
NCT03364621 ·Status: ACTIVE_NOT_RECRUITING
-
Detecting Colorectal Cancer With Liver Metastatic Lesions Using Novel Precise Imaging Tools
NCT06935149 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer
NCT00002997 ·Status: COMPLETED ·Phase: PHASE2
-
Management of Metastatic Colorectal Cancer: A Clinical and Patient Perspective
NCT03935763 ·Status: ACTIVE_NOT_RECRUITING
-
Detection Rate of Liver Metastases With Contrast Enhanced Intraoperative Ultrasound Compared to Regular Imaging
NCT01522209 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Preoperative Investigations in Patients With Liver Cancer
NCT00408122 ·Status: COMPLETED
-
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
NCT06698146 ·Status: RECRUITING
-
Living Donor Liver Transplantation for CRC Liver Metastases
NCT05175092 ·Status: WITHDRAWN ·Phase: NA
-
Resection of Colorectal Liver Metastases With or Without Routine Hilar Lymphadenectomy
NCT01073358 ·Status: UNKNOWN ·Phase: NA