Investigating the Clinical Consequences of Flutemetamol-PET-scanning
NCT02353949 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 11
Last updated 2020-01-21
Summary
The study examines subjects where there might be an indication for Amyloid-PET according to the Criteria defined by the Amyloid Imaging Task Force. In these subjects the impact of a Flutemetamol (Vizamyl)-Positron-Emission-Tomography -Scan (PET) on clinical management and disease course will be studied over 6 months.
Conditions
Interventions
- DRUG
-
Flutemetamol (Vizamyl)
PET-MR Scan using the radiotracer Flutemetamol (Vizamyl) for diagnostic purpose
Sponsors & Collaborators
-
ETH Zurich
collaborator OTHER -
University of Zurich
lead OTHER
Principal Investigators
-
Christoph Hock, MD, Prof. · University of Zurich, Institute for Regenerative Medicine, Center for Prevention and Dementia Therapy
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-05-31
- Primary Completion
- 2019-12-10
- Completion
- 2019-12-10
Countries
- Switzerland
Study Locations
More Related Trials
-
Practice Effects and Amyloid Imaging Using 18F-PIB or Flutemetamol PET and FDG-PET
NCT01202994 ·Status: COMPLETED ·Phase: PHASE2
-
Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl
NCT06439992 ·Status: RECRUITING
-
Initial Investigation of [18F]P16-129 in Alzheimer's Disease Patients and Healthy Volunteers
NCT03902548 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase IIa Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease
NCT02167256 ·Status: COMPLETED ·Phase: PHASE2
-
PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)
NCT07169630 ·Status: RECRUITING ·Phase: PHASE1
-
Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation
NCT02149160 ·Status: UNKNOWN ·Phase: PHASE2
-
Early Diagnosis and Early Treatment of Alzheimer's Disease Based on Senile Plaque Imaging
NCT02931136 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease
NCT04468347 ·Status: COMPLETED ·Phase: PHASE1
-
Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy
NCT00499200 ·Status: COMPLETED ·Phase: PHASE1
-
A PET Study of the Effects of p38 MAP Kinase Inhibitor, VX-745, on Amyloid Plaque Load in Alzheimer's Disease (AD)
NCT02423122 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Two Doses of 18F-AV-45 in Alzheimer's Disease and Healthy Volunteers
NCT01565330 ·Status: COMPLETED ·Phase: PHASE1
-
Registry of Amyloid Positive Patients for Alzheimer's Disease Drug Research Trials
NCT02918539 ·Status: COMPLETED
-
Phase 1 and Phase 2 Clinical Trials of SNUBH-NM-333(18F)
NCT02149017 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Evaluation of ZK 6032924 in Probable Alzheimer's Disease Patients Versus Healthy Volunteers and the Radiation Dosimetry of ZK 6032924 in Healthy Volunteers
NCT01035164 ·Status: COMPLETED ·Phase: PHASE1
-
Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to Histopathology
NCT01020838 ·Status: COMPLETED ·Phase: PHASE3
-
Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy Volunteers
NCT00750282 ·Status: COMPLETED ·Phase: PHASE2
-
A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol
NCT03274817 ·Status: TERMINATED ·Phase: PHASE1
-
An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.
NCT00474513 ·Status: COMPLETED ·Phase: PHASE1
-
A Preliminary Study of 18F-AV-45 in Alzheimer's Disease and Healthy Elderly Volunteers
NCT01565291 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Therapeutic Efficacy of Monoclonal Antibody Drugs for Alzheimer's Disease Based on PET Research
NCT07152418 ·Status: NOT_YET_RECRUITING
-
Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease
NCT01028053 ·Status: COMPLETED ·Phase: PHASE3
-
Phase III Study of the Correlation Between Florbetapir F18 PET Imaging and Amyloid Pathology in the Brain
NCT00857415 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I [18F]THK-5351 Positron Emission Tomography Study in Healthy Subjects and Alzheimer's Disease
NCT03112096 ·Status: COMPLETED ·Phase: PHASE1
-
Positron Emission Tomography Study Using 2-[18F]-F-A85380 to Determine α4β2 Neuronal Nicotinic Receptor Occupancy of AZD3480 After Oral Administration to Healthy Male Subjects
NCT00686413 ·Status: COMPLETED ·Phase: PHASE1
-
Bridging Study of C11 Pittsburgh Compound B (PiB) and F18 Flutemetamol Brain Positron Emission Tomography (PET)
NCT01607476 ·Status: COMPLETED ·Phase: PHASE2