Effects of Acute Estrogen Therapy on Bone Formation
NCT02349113 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2015-02-16
Summary
This study is being done to study age-related bone changes in women. The investigators know that the major cause of osteoporosis is a shortage of the female hormone estrogen. This study will look closer at how this shortage of estrogen works to cause a decrease in bone formation.
Conditions
- Bone Loss, Age-related
Interventions
- DRUG
-
Estrogens (Climara)
Treatment with estrogens: Estradiol dermal patch 0.1mg/d transdermally
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Sundeep Khosla, MD · Mayo Clinic
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 65 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-02-29
- Primary Completion
- 2012-09-30
- Completion
- 2012-09-30
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