Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss
NCT00004650 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2005-06-24
Summary
OBJECTIVES: I. Quantify periodontal alveolar bone loss rates in postmenopausal women.
II. Evaluate the effects of estrogen on alveolar bone loss rates in these patients.
III. Determine whether changes in periodontal bone mass relate to bone mass changes in other skeletal sites in these patients.
Conditions
Interventions
- DRUG
-
conjugated estrogens
- DRUG
-
Medroxyprogesterone
Sponsors & Collaborators
-
Washington University School of Medicine
collaborator OTHER -
National Institute of Dental and Craniofacial Research (NIDCR)
lead NIH
Principal Investigators
-
Charles F. Hildebolt · Washington University School of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
Eligibility
- Min Age
- 0 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1993-08-31
More Related Trials
-
A Study to Evaluate and Compare Alendronate and Risedronate on Bone Mineral Density in Women With Postmenopausal Osteoporosis (MK-0217-211)
NCT00092014 ·Status: COMPLETED ·Phase: PHASE3
-
Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinical Trial
NCT00354302 ·Status: COMPLETED ·Phase: PHASE3
-
Alendronate and/or Parathyroid Hormone for Osteoporosis
NCT00000400 ·Status: COMPLETED ·Phase: PHASE2
-
Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density
NCT00431444 ·Status: COMPLETED ·Phase: PHASE4
-
Calcium With or Without Estrogen and/or Risedronate in Preventing Osteoporosis in Patients With Prostate Cancer
NCT00043069 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Phytoestrogen-rich Diets on Bone Turnover in Postmenopausal Women
NCT00301353 ·Status: COMPLETED ·Phase: NA
-
Dietary Phytoestrogens and Bone Metabolism
NCT00010686 ·Status: COMPLETED ·Phase: PHASE2
-
Rhythmic Estradiol and Bone Health
NCT05903820 ·Status: COMPLETED ·Phase: PHASE4
-
Can Parathyroid Hormone Injections Reverse Glucocorticoid-induced Osteoporosis
NCT00004993 ·Status: COMPLETED ·Phase: PHASE2
-
Bone Turnover Markers and Treatment Efficacy in Postmenopausal Osteoporosis
NCT07242612 ·Status: RECRUITING ·Phase: NA
-
Phase 2 Safety and Efficacy Study of a Vitamin D Compound (DP001) in Postmenopausal Women With Low Bone Mineral Density
NCT00715676 ·Status: COMPLETED ·Phase: PHASE2
-
A Study and 12 Month Extension to Evaluate Two Investigational Drugs in Postmenopausal Women With Osteoporosis (MK-0217-907)
NCT00092040 ·Status: COMPLETED ·Phase: PHASE3
-
Determine the Efficacy, Safety and Tolerability of Denosumab (AMG 162) in the Treatment of Postmenopausal Women With Low Bone Mineral Density
NCT00043186 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin K and Bone Turnover in Postmenopausal Women
NCT00062595 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Test the Effect of MK0217A on Vitamin D Inadequacy in Postmenopausal Women With Osteoporosis (0217A-262)
NCT00692913 ·Status: COMPLETED ·Phase: PHASE3
-
MK-5442 in the Treatment of Osteoporosis in Postmenopausal Women Previously Treated With an Oral Bisphosphonate (MK-5442-012)
NCT00996801 ·Status: COMPLETED ·Phase: PHASE2
-
Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women
NCT00504166 ·Status: COMPLETED ·Phase: PHASE4
-
Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-menopausal Women With Low Bone Mass
NCT00489424 ·Status: COMPLETED ·Phase: PHASE4
-
An Open-label, Single-arm Extension Study to Evaluate the Long-term Safety of Denosumab Administration in Postmenopausal Women With Low Bone Mineral Density
NCT00325468 ·Status: COMPLETED ·Phase: PHASE3
-
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
NCT00330460 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate AMG 162 in the Prevention of Postmenopausal Osteoporosis
NCT00091793 ·Status: COMPLETED ·Phase: PHASE3
-
Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
NCT00443716 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density
NCT01406548 ·Status: COMPLETED ·Phase: PHASE2
-
Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women
NCT00086619 ·Status: COMPLETED ·Phase: PHASE2
-
Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
NCT00290212 ·Status: COMPLETED ·Phase: PHASE2