Phase II Study of Pazopanib and Topotecan in Cervical Cancer
NCT02348398 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2016-08-16
Summary
The goal of this clinical research study is to learn if the combination of topotecan and pazopanib can help to control recurrent cervical cancer. The safety of the study drug combination will also be studied.
Conditions
Interventions
- DRUG
-
Pazopanib
600 mg by mouth daily in a 28 day cycle.
- DRUG
-
Topotecan
0.25 mg by mouth daily for 21 days of a 28 day cycle.
- BEHAVIORAL
-
Phone Call
During follow up if disease gets worse, participant called by study staff every 3 months. Each call should last about 5 minutes.
Sponsors & Collaborators
- collaborator INDUSTRY
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Michael M. Frumovitz, MD, MPH · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2019-08-31
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