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High-Dose Brachytherapy in Treating Patients With Prostate Cancer

NCT02346253 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 146

Last updated 2026-04-13

No results posted yet for this study

Summary

This trial studies the side effects and how well high-dose brachytherapy works in treating patients with prostate cancer that has not spread to other parts of the body. Brachytherapy is a type of radiation therapy in which radioactive material sealed in needles, seeds, wires, or catheters is placed directly into or near a tumor and may be a better treatment in patients with prostate cancer.

Conditions

  • Prostate Adenocarcinoma
  • Stage I Prostate Cancer
  • Stage IIA Prostate Cancer
  • Stage IIB Prostate Cancer
  • Stage III Prostate Cancer

Interventions

RADIATION

Internal Radiation Therapy

Undergo high-dose-rate brachytherapy

DRUG

Bicalutamide

Given PO

DRUG

Leuprolide Acetate

Given IM or SC

DRUG

Goserelin Acetate

Given SC

DRUG

Triptorelin Pamoate

Given IM

DRUG

Degarelix

Given SC

OTHER

Laboratory Biomarker Analysis

Correlative studies

OTHER

Quality-of-Life Assessment

Ancillary studies

Sponsors & Collaborators

Principal Investigators

  • Mark Buyyounouski · Stanford University Hospitals and Clinics

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-13
Primary Completion
2021-12-14
Completion
2026-05-17

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02346253 on ClinicalTrials.gov