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Comparison of Non-invasive Measurement Methods of Hepatic Fibrosis in Cystic Fibrosis

NCT02342964 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2025-11-20

No results posted yet for this study

Summary

Non-invasive methods of the quantification of fibrosis may help to assess the development of fibrosis at a specific moment of the evolution of the disease, in the order to decide the initiation of treatment with ursodeoxycholic acid which may slow the progression to hepatic cirrhosis:

* FibroTest,
* The ultrasound impulse elastography, Fibroscan (FS)
* Ultrasound Elastography by ShearWave (SWE)
* Magnetic resonance elastography (MRE). The purpose of this study is to assess the contribution of these methods in the diagnosis of hepatic fibrosis during the evolution of the cystic fibrosis.

Conditions

Interventions

OTHER

Measure of hepatic elasticity

Measure of hepatic elasticity by four non-invasive methods: Fibroscan, Fibrotest, SWE, MRE.

Sponsors & Collaborators

  • Vaincre la Mucoviscidose

    collaborator OTHER

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Dominique Debray, MD, PhD · 00 33 1 44 49 41 52

Study Design

Allocation
NA
Purpose
SCREENING
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
6 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-08
Primary Completion
2019-01-31
Completion
2019-01-24

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02342964 on ClinicalTrials.gov