Psychometric Properties Mobility Measures MS

Summary

Current study will investigate the quality (psychometric properties) and clinical utility of several mobility measures, according to disability level. Therefore, several aspects will be inquired:

* Was there an effect of rehabilitation
* Is the measure able to detect change over time? And thus the change exceed measurement error and is it clinically important (responsiveness)
* Does the measure assess what it claims to measure (validity)
* Is the measure able to differentiate all performances of the patients, inclusively the very good and very bad performances (floor and ceiling effects)
* Does the measure gives similar results under consistent test conditions on another testing day (reliability) Worldwide, theoretical approaches to physical therapy and rehabilitation in Multiple Sclerosis often appear significantly different. Since the present research protocol will be performed at different centers across European countries (and US sites), this multi-center study can additionally be applied for mapping the volume and content of rehabilitation, as well as the differential impact of diverse rehabilitation approaches and training volume on mobility, for several disability levels.

Some health-economic analyses will be performed to examine what the approximate cost of rehabilitation compared to effects is and what drivers of costs are (setting, equipment, staff).

Conditions

• Multiple Sclerosis

Interventions

OTHER

conventional MS rehabilitation

assessment pre and post conventional MS rehabilitation

Sponsors & Collaborators

• Dept Neurological Rehabilitation Reha Zentrum Münster Gröben

  collaborator UNKNOWN

• National MS Center Melsbroek

  collaborator OTHER

• Revalidatie & MS Centrum Overpelt

  collaborator OTHER

• De Mick

  collaborator UNKNOWN

• Charles University, Czech Republic

  collaborator OTHER

• Danish MS Hospitals, Haslev and Ry

  collaborator OTHER

• Masku Neurological Rehabilitation Center

  collaborator UNKNOWN

• Quellenhof

  collaborator UNKNOWN

• Fondazione Don Carlo Gnocchi Onlus

  collaborator OTHER

• Italian Multiple Sclerosis Foundation

  collaborator OTHER

• Sheba Medical Center

  collaborator OTHER_GOV

• MS-Senteret Hakadal

  collaborator UNKNOWN

• Haukeland University Hospital

  collaborator OTHER

• MS Rehabilitation Center Borne Sulinowo

  collaborator UNKNOWN

• Clinical center Belgrado

  collaborator UNKNOWN

• Eugenia Epalza Rehabilitation Center, Bilbao, Spain

  collaborator OTHER

• Cleveland Mellen MS Center

  collaborator UNKNOWN

• University of Colorado, Denver

  collaborator OTHER

• Queen's University

  collaborator OTHER

• Shepherd Center Atlanta

  collaborator UNKNOWN

• St. Louis University

  collaborator OTHER

• Hasselt University

  lead OTHER

Principal Investigators

• Peter Feys, prof. dr. · Hasselt University

• Ilse Baert · Hasselt University

Study Design

Allocation

NA

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2015-12-31

Completion

2016-06-30

Countries

• Belgium

Study Locations