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Transcutaneous-Arterial Carbon Dioxide and Microcirculatory Dysfunction

NCT02328846 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2018-10-22

No results posted yet for this study

Summary

Evaluation of the microcirculation is currently limited. Continual assessment of the tissue carbon dioxide-arterial carbon dioxide (PtC02-aCO2) offers a new, novel and noninvasive method of determining the state of the microcirculation. The investigators will apply two non-invasive devices, the Braedius sidesteam darkfield microscopy (SDF) microscopy device to the sublingual circulation and the transcutaneous PtC02 probe to the forehead in subjects undergoing cardiac surgery with cardiopulmonary bypass. The PtC02-aCO2 gradient will be determined and correlated with the videomicroscopic images of the sublingual microcirculation. Thereafter the incidence of postoperative organ failure and acute kidney injury will be determined and correlated with PtC02-arterial CO2 gradient and videomicroscopic images.

Data will be analyzed by standard descriptive statistical methods.

Conditions

  • Bypass Complications

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Bhiken I Naik, M.B.B.Ch · University of Virginia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-31
Primary Completion
2019-01-31
Completion
2020-02-29

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02328846 on ClinicalTrials.gov