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Clinical & Visual Outcomes of Collagen Cross Linking for Fungal Keratitis

NCT02328053 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2014-12-31

No results posted yet for this study

Summary

The study is a randomised control trial to assess the visual and clinical outcomes of collagen cross linking in fungal keratitis. Fungal keratitis is a major cause of corneal blindness in India and the therapeutic options available are minimal to handle the advanced complications and sequalae caused by the disease.The antimicrobial and tissue remodeling role of corneal cross linking was demonstrated by several studies earlier,we anted to specifically assess the role of corneal cross linking in non resolving fungal keratitis in prevention of perforation and enhancement of healing process.

Conditions

  • Mycotic Corneal Ulcer

Interventions

PROCEDURE

collagen crosslinking group

collagen crosslinking with riboflavin and Ultraviolet A

DRUG

Topical anti-fungal therapy

topical antifungal medications like natamycin eye drops and voriconazole eye drops

Sponsors & Collaborators

  • Aravind Eye Care System

    lead OTHER

Principal Investigators

  • Dr. Venkatesh Prajna, DNB,FRCS · CHIEF CORNEA SERVICES

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-07-31
Completion
2015-09-30

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02328053 on ClinicalTrials.gov