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DEtection of Cellular Inflammation With FERumoxytol in the HEART

NCT02319278 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 58

Last updated 2017-05-03

No results posted yet for this study

Summary

To non-invasively image myocardial accumulation of ultrasmall superparamagnetic particles of iron oxide (USPIOs) by an increase in R2\* values (compared to controls) within the myocardium of patients with:

i. cardiac transplantation ii. acute myocarditis iii. suspected cardiac sarcoidosis

Conditions

  • Cardiac Transplant
  • Cardiac Sarcoid
  • Myocarditis
  • Healthy Volunteers

Interventions

DRUG

Ferumoxytol

Infusion following between paired MRI scans

Sponsors & Collaborators

  • Royal Infirmary of Edinburgh

    collaborator OTHER

  • Golden Jubilee National Hospital

    collaborator OTHER_GOV

  • Royal Brompton & Harefield NHS Foundation Trust

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Colin Stirrat, MBChB · University of Edinburgh

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2016-11-30
Completion
2016-11-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02319278 on ClinicalTrials.gov