Study of the Role of Regulator T Cells in the Pathophysiology of Childhood Henoch Schönlein Purpura
NCT02317133 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-11-19
Summary
The primary objective of this study is to search for evidence of quantitative or functional defects in plasma regulatory T cells (Tregs) in pediatric patients with Henoch Schönlein Purpura (HSP) as compared to a control population.
Conditions
- Henoch Schönlein Purpura
Interventions
- BIOLOGICAL
-
Blood samples
Compared to routine practice, 3 additional tubes of blood will be drawn for the observational needs of this study.
- BIOLOGICAL
-
Stool samples
Stool samples will be collected for the observational needs of this study (and are not part of routine practice).
Sponsors & Collaborators
-
Centre Hospitalier Universitaire de Nīmes
lead OTHER
Principal Investigators
-
Tu Anh Tran, MD, PhD · Centre Hospitalier Universitaire de Nîmes
Eligibility
- Min Age
- 3 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-02-28
- Primary Completion
- 2017-07-12
- Completion
- 2017-07-12
Countries
- France
Study Locations
More Related Trials
-
Efficacy and Safety of IVIG-L in ITP Patients
NCT00151840 ·Status: COMPLETED ·Phase: PHASE3
-
Steroid Resistance in Pediatric Immune Thrombocytopenic Purpura
NCT06601543 ·Status: NOT_YET_RECRUITING
-
Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP)
NCT06945861 ·Status: RECRUITING
-
An Epidemiological Study of Subjects With Immune Thrombocytopenic Purpura to Evaluate the Relationship Between Platelet Counts, Endogenous Thrombopoietin Levels, Endogenous Anti-Thrombopoietin Antibodies, and Selected Autoimmune Markers
NCT00005570 ·Status: COMPLETED
-
NATURAL KILLER CELLS IN IMMUNOLOGIC THROMBOCYTOPENIC PURpura of Adults
NCT01172015 ·Status: COMPLETED ·Phase: NA
-
The Outcome of the Thrombopoietin Receptor Agonists in Pediatric Patient With Persistent or Chronic ITP Unresonsive to Steroids
NCT06568913 ·Status: RECRUITING ·Phase: NA
-
Health-related Quality of Life and Fatigue in Adult Patients With Primary Immune Thrombocytopenic Purpura (pITP)
NCT01510873 ·Status: COMPLETED
-
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-schönlein Purpura
NCT04387942 ·Status: COMPLETED ·Phase: NA
-
Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients
NCT03866577 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Rituximab in Adult Acquired Idiopathic Thrombotic Thrombocytopenic Purpura
NCT00907751 ·Status: COMPLETED ·Phase: PHASE2
-
Research of Predictive Factors to Immune Thrombopenic Purpura
NCT01648556 ·Status: COMPLETED ·Phase: NA
-
A Study Evaluating the Safety and Efficacy of Long-term Dosing of Romiplostim in Thrombocytopenic Pediatric Patients With Immune (Idiopathic) Thrombocytopenia Purpura
NCT01071954 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Adult Subjects With Chronic Idiopathic Thrombocytopenic Purpura
NCT00162006 ·Status: COMPLETED ·Phase: PHASE2
-
Prophylactic Plasma Infusion Therapy for Congenital Thrombotic Thrombocytopenic Purpura
NCT01754545 ·Status: WITHDRAWN ·Phase: PHASE4
-
Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
NCT00454857 ·Status: COMPLETED
-
Immune Markers in Pediatric ITP on Second Line Therapy
NCT06093529 ·Status: NOT_YET_RECRUITING
-
Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)
NCT05371743 ·Status: UNKNOWN
-
Study of the Effectiveness of Rituximab in Adults With Chronic and Severe Immune Thrombocytopenic Purpura and Candidate for a Splenectomy
NCT00225875 ·Status: TERMINATED ·Phase: PHASE2
-
Retrospective Analysis of the Safety and Efficacy of Hydroxychloroquine in Immune Thrombocytopenia
NCT01549184 ·Status: COMPLETED
-
The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)
NCT06291415 ·Status: WITHDRAWN ·Phase: PHASE1
-
Longitudinal Cohort of Pediatric Primary Immune Thrombocytopenia (ITP)
NCT06107582 ·Status: RECRUITING
-
"Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4) Gene Single-nucleotide Polymorphism in Primary Immune Thrombocytopenic Purpura in Children"
NCT07014904 ·Status: NOT_YET_RECRUITING
-
Prevalence of Thyroid Disorders in Patients With Immune Thrombocytopenic Purpura and Its Impact on Treatment
NCT07059910 ·Status: NOT_YET_RECRUITING
-
National Prospective Cohort for Monitoring Children With Severe Autoimmune Cytopenia.
NCT04070612 ·Status: COMPLETED
-
Observatory of Immunological Thrombopenic Purpura in the Brest Region
NCT06556888 ·Status: RECRUITING