The Effect of Vitamin B3 on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men
NCT02303483 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2017-07-02
Summary
In animals, treatment with vitamin B3 improved insulin sensitivity and substrate metabolism. It is currently not know if vitamin B3 has the same positive effects in humans. In the current study the effect of a 3 month treatment with vitamin B3 on insulin sensitivity and substrate metabolism in obese men will be investigated.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Nicotinamide riboside (NIAGEN TM, ChromaDex, CA, USA )
- DIETARY_SUPPLEMENT
-
Placebo
Sponsors & Collaborators
-
University of Copenhagen
collaborator OTHER -
Aarhus University Hospital
lead OTHER
Principal Investigators
-
Ole Dollerup, MD · The Novo Nordisk Foundation Center for Basic Metabolic Research, Integrative Physiology, University of Copenhagen
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 70 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-01-04
- Primary Completion
- 2017-04-04
- Completion
- 2017-04-04
Countries
- Denmark
Study Locations
More Related Trials
-
Lean Beef Consumption and Insulin Sensitivity in Men and Women With Risk Factors for Diabetes
NCT03202680 ·Status: COMPLETED ·Phase: NA
-
The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion
NCT01056497 ·Status: COMPLETED ·Phase: PHASE4
-
A Clinical Trial to Assess the Efficacy and Tolerance of a Berberine-based Nutraceutical Formula to Aid Blood Sugar Regulation and Metabolism
NCT06700915 ·Status: RECRUITING ·Phase: NA
-
Prevention of Maternal and Fetal Metabolic Complications With Diet and Nutraceutical Supplementation in Pregnant Women Affected by Gestational Diabetes: a Randomized, Double-blind Placebo Controlled Trial.
NCT05393843 ·Status: TERMINATED ·Phase: PHASE4
-
Nutritional Supplementation and Insulin Sensitivity
NCT04239482 ·Status: TERMINATED ·Phase: NA
-
The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes
NCT04163757 ·Status: COMPLETED ·Phase: NA
-
Impact of Alpha-Lipoic Acid Ingestion on Glucose Tolerance in Subjects With Pre-Diabetes
NCT03612037 ·Status: COMPLETED ·Phase: NA
-
Effects of Corn and Coconut Oils on Lipoprotein Lipids, Insulin Sensitivity and Inflammation
NCT03202654 ·Status: COMPLETED ·Phase: NA
-
n-3 Fatty Acid Infusion and Type 2 Diabetes
NCT00829569 ·Status: COMPLETED ·Phase: NA
-
Glycemic Response to Oral Nutrition Supplements
NCT02612675 ·Status: COMPLETED ·Phase: NA
-
The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
NCT01738802 ·Status: COMPLETED ·Phase: NA
-
A Study to Determine the Safety and Tolerability of a Range of Doses of PeptiControl in Pre-diabetic Individuals
NCT06440213 ·Status: COMPLETED ·Phase: NA
-
The Impact of Vitamins and Minerals Supplementation on Neuropathy and Nephropathy Complications
NCT01173315 ·Status: COMPLETED ·Phase: PHASE2
-
Role of Slowly Digesible Starch on Diabetes Risk Factors
NCT01708694 ·Status: COMPLETED ·Phase: NA
-
Effects of Micronutrient (Chromium) Supplementation on Diabetes
NCT01709123 ·Status: COMPLETED ·Phase: NA
-
Pilot Study on Metabolic Effects of Fish Peptides and Vitamin D
NCT02668159 ·Status: COMPLETED ·Phase: NA
-
Isoleucine Intake and Intermediary Metabolism in Type 2 Diabetes
NCT04461236 ·Status: COMPLETED ·Phase: NA
-
Effect of Oral L-arginine 3.32 g a Day on Oxidative Stress Influencing Beta Cell Function and Insulin Resistance.
NCT06686069 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Efficacy and Safety Study of Chromium Picolinate + Biotin on Glucose and Cholesterol Control in T2DM
NCT00289354 ·Status: COMPLETED ·Phase: NA
-
Effects of Vitamin D on Beta Cell Function and Insulin Sensitivity in Pre-diabetes and Diabetes Mellitus Type 2
NCT01497132 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of a Dietary Supplement on Markers of Glucose Control and Quality of Life
NCT05573607 ·Status: COMPLETED ·Phase: NA
-
Effect of Omega-3 Fatty Acids on Insulin Sensitivity in Chinese Type 2 Diabetic Patients
NCT01857167 ·Status: COMPLETED ·Phase: NA
-
Effect of the Chromium Nicotinate on Type 2 Diabetes
NCT01368328 ·Status: UNKNOWN ·Phase: PHASE3
-
The Effect of a Nutritional Supplement in Individuals With Type 2 Diabetes Mellitus: a Pilot Study
NCT01505803 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of a Nutritional Supplement for People With Type 2 Diabetes.
NCT01850134 ·Status: WITHDRAWN ·Phase: NA