Cerebellar Mutism Syndrome Study

Summary

The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.

Conditions

• Infratentorial Neoplasms
• Mutism

Sponsors & Collaborators

• Odense University Hospital

  collaborator OTHER

• Aarhus University Hospital

  collaborator OTHER

• Aalborg University Hospital

  collaborator OTHER

• Technical University of Denmark

  collaborator OTHER

• Karolinska University Hospital

  collaborator OTHER

• Skane University Hospital

  collaborator OTHER

• University Hospital, Linkoeping

  collaborator OTHER

• Uppsala University Hospital

  collaborator OTHER

• Sahlgrenska University Hospital

  collaborator OTHER

• University Hospital, Umeå

  collaborator OTHER

• Oslo University Hospital

  collaborator OTHER

• Trondheim University Hospital

  collaborator OTHER

• Haukeland University Hospital

  collaborator OTHER

• University Hospital of North Norway

  collaborator OTHER

• Helsinki University Central Hospital

  collaborator OTHER

• Tampere University Hospital

  collaborator OTHER

• Kuopio University Hospital

  collaborator OTHER

• Turku University Hospital

  collaborator OTHER_GOV

• Oulu University Hospital

  collaborator OTHER

• Radboud University Medical Center

  collaborator OTHER

• Liverpool University Hospitals NHS Foundation Trust

  collaborator OTHER_GOV

• Great Ormond Street Hospital for Children NHS Foundation Trust

  collaborator OTHER

• Nottingham University Hospitals NHS Trust

  collaborator OTHER

• University Hospital Birmingham

  collaborator OTHER

• University Hospitals Bristol and Weston NHS Foundation Trust

  collaborator OTHER

• Royal Infirmary of Edinburgh

  collaborator OTHER

• South Glasgow University Hospitals NHS Trust

  collaborator OTHER

• University Hospital Tuebingen

  collaborator OTHER

• Medical University of Vienna

  collaborator OTHER

• Ospedale Pediatrico Bambin Gesù

  collaborator OTHER

• Motol University Hospital

  collaborator OTHER

• University of Leipzig Medical Center

  collaborator UNKNOWN

• Universitaire Ziekenhuizen KU Leuven

  collaborator OTHER

• Queen Fabiola Children's University Hospital

  collaborator OTHER

• Cliniques universitaires Saint-Luc- Université Catholique de Louvain

  collaborator OTHER

• University Hospital, Ghent

  collaborator OTHER

• Hospital De La Citadelle

  collaborator UNKNOWN

• CHC MontLégia

  collaborator UNKNOWN

• University Hospital, Antwerp

  collaborator OTHER

• Hospital Sant Joan de Deu

  collaborator OTHER

• Vienna University Hospital, Austria

  collaborator UNKNOWN

• Rigshospitalet, Denmark

  lead OTHER

Principal Investigators

• Kjeld Schmiegelow, MD, Dr. med · Rigshospitalet, Denmark

• Marianne Juhler, MD, Dr. med · Rigshospitalet, Denmark

• Karsten Nysom, MD · Rigshospitalet, Denmark

Eligibility

Max Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2028-12-31

Completion

2028-12-31

Countries

• Austria
• Belgium
• Czechia
• Denmark
• Finland
• Germany
• Hungary
• Italy
• Lithuania
• Netherlands
• Norway
• Sweden
• United Kingdom

Study Locations