Impact of Hybrid Coronary Revascularization on Antiplatelet Therapy
NCT02293928 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2014-11-19
Summary
The effect of antiplatelet therapy is impaired among patients, who recently underwent on-pump coronary artery bypass grafting. The impact of hybrid coronary revascularization using minimal invasive surgical techniques on the antiplatelet effect of aspirin and clopidogrel remains unclear.
The aim of the study is to describe the impact of hybrid coronary revascularization on the effect of aspirin and clopidogrel. Furthermore, we will investigate whether high baseline platelet aggregation, high postoperative levels of platelet turnover and acute-phase response may contribute to the effect.
Conditions
Interventions
- PROCEDURE
-
Hybrid coronary revascularization
Hybrid coronary revascularization with standard double antiplatelet therapy
Sponsors & Collaborators
-
Danish Heart Foundation
collaborator OTHER -
Aase and Ejnar Danielsens Foundation
collaborator OTHER -
Aarhus University Hospital Skejby
lead OTHER
Principal Investigators
-
Ivy S Modrau, MD, DMSc · Aarhus University Hospitak Skejby
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-10-31
- Primary Completion
- 2013-04-30
- Completion
- 2013-04-30
Countries
- Denmark
Study Locations
More Related Trials
-
Modified-release Dipyridamole/Aspirin (200mg/25mg bd) Versus Aspirin (75mg) in Aspirin-resistant Patients
NCT00129038 ·Status: COMPLETED ·Phase: PHASE4
-
Optimum Platelet Inhibition After Coronary Bypass Surgery
NCT00262275 ·Status: COMPLETED ·Phase: NA
-
Impact of Combination of Clopidogrel With Aspirin on Postoperative Bleeding in Coronary Surgical Patients
NCT01216150 ·Status: COMPLETED
-
Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement
NCT00465218 ·Status: COMPLETED
-
A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary Syndrome
NCT02293395 ·Status: COMPLETED ·Phase: PHASE2
-
Aspirin Responsiveness and Outcome in Coronary Artery Bypass Graft (CABG) Surgery
NCT01174862 ·Status: COMPLETED
-
Reversal of Dual Antiplatelet Therapy With Cold Stored Platelets
NCT03787927 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
The Effects of Preoperative Aspirin on Graft Patency and Cardiac Events in Off-pump Coronary Artery Bypass
NCT01268917 ·Status: UNKNOWN ·Phase: PHASE3
-
Ticagrelor and Aspirin for the Prevention of Cardiovascular Events After Coronary Artery Bypass Surgery
NCT01373411 ·Status: COMPLETED ·Phase: PHASE4
-
Ticagrelor-Based Dual Antiplatelet Therapy Duration in CABG
NCT06981390 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study Comparing Ticagrelor With Aspirin for Prevention of Vascular Events in Patients Undergoing CABG
NCT01755520 ·Status: TERMINATED ·Phase: PHASE3
-
Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel
NCT02032290 ·Status: UNKNOWN ·Phase: PHASE4
-
Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation
NCT02247128 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacodynamic Effects of Dabigatran in Patients on Dual Antiplatelet Therapy
NCT01852162 ·Status: COMPLETED ·Phase: NA
-
The Effect of Clopidogrel and Ticagrelor With and Without Acetylsalicylic Acid (ASA) on Hemostatic System Activation at the Site of Plug Formation in Vivo in Man
NCT02120092 ·Status: COMPLETED ·Phase: PHASE2
-
Rivaroxaban or Aspirin for Biological Aortic Prosthesis
NCT02974920 ·Status: UNKNOWN ·Phase: PHASE4
-
Treatment With Aspirin Alone Versus Aspirin in Combination With Fondaparinux Before Early Coronary Assessment in Patients With Non-ST-Elevation Myocardial Infarction
NCT06710184 ·Status: RECRUITING ·Phase: PHASE4
-
Aspirin vs Clopidogrel After TAVR
NCT05493657 ·Status: RECRUITING ·Phase: NA
-
Aspirin Resistance Following Coronary Bypass Surgery
NCT00260377 ·Status: TERMINATED ·Phase: NA
-
Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis
NCT02022527 ·Status: UNKNOWN ·Phase: PHASE4
-
Optimized Antiplatelet Therapy on the Prognosis of ACS Patients With Non-predominant Coronary Artery Disease After PCI
NCT04338919 ·Status: UNKNOWN ·Phase: NA
-
Aspirin Response in High Risk Patients With Coronary Artery Disease
NCT01383304 ·Status: UNKNOWN
-
Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen
NCT03023020 ·Status: COMPLETED ·Phase: NA
-
Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation
NCT01938248 ·Status: COMPLETED ·Phase: PHASE4
-
The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack
NCT02144831 ·Status: WITHDRAWN ·Phase: PHASE4