Optimum Platelet Inhibition After Coronary Bypass Surgery
NCT00262275 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL
Last updated 2016-01-22
Summary
To investigate the effect of different dosages of aspirin on platelet aggregation and to determine the possible mechanisms of aspirin resistance, we intend to compare the effects of low, medium dose aspirin with clopidogrel (an alternative antiplatelet agent) in patients after coronary artery bypass surgery.
Conditions
- Ischemic Heart Disease
Interventions
- DRUG
-
Aspirin, Clopidogrel
Sponsors & Collaborators
-
Papworth Hospital NHS Foundation Trust
lead OTHER_GOV
Principal Investigators
-
Eric Lim, MB ChB, MSc, MRCS · Papworth Hospital NHS Foundation Trust
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-07-31
- Primary Completion
- 2004-07-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Effects of Low Dose Aspirin Pre-treatment on Platelet Activation Undergoing Off-pump Coronary Artery Bypass Surgery
NCT02209909 ·Status: COMPLETED ·Phase: NA
-
Aspirin Resistance Following Coronary Bypass Surgery
NCT00260377 ·Status: TERMINATED ·Phase: NA
-
Aspirin Responsiveness and Outcome in Coronary Artery Bypass Graft (CABG) Surgery
NCT01174862 ·Status: COMPLETED
-
Optimal PERioperative Antiplatelet Therapy Investigation ON Abdominal Surgery After Coronary Stent Implantation
NCT06723145 ·Status: RECRUITING ·Phase: PHASE4
-
Efficacy and Safety of Aspirin and Clopidogrel in the Atrial Fibrillation With Low or Moderate Stroke Risk
NCT02960126 ·Status: UNKNOWN ·Phase: PHASE3
-
PPARGC1β and CNTN4 Genotype Aspirin Study
NCT02970604 ·Status: UNKNOWN ·Phase: PHASE4
-
Optimizing Aspirin and Clopidogrel Therapy (BOchum CLopidogrel and Aspirin Plan)
NCT01212302 ·Status: COMPLETED ·Phase: NA
-
WILL lOWer Dose Aspirin be Better With Rivaroxaban in Patients With Chronic Coronary Syndromes?
NCT04990791 ·Status: COMPLETED ·Phase: PHASE4
-
Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery
NCT02201771 ·Status: COMPLETED ·Phase: PHASE4
-
Antiplatelet Therapy Continuation in Spine Surgery - Its Effect on Postoperative Morbidity and Mortality
NCT01006083 ·Status: UNKNOWN
-
ASA- and Clopidogrel-Responsiveness in Patients With Peripheral Arterial Occlusive Disease and Interventional Procedures
NCT00593762 ·Status: SUSPENDED
-
Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For VTE Following Total Joint Arthroplasty
NCT04295486 ·Status: RECRUITING ·Phase: PHASE2
-
Perioperative Aspirin Response in Patients Undergoing Vascular Surgery
NCT03587324 ·Status: COMPLETED ·Phase: NA
-
A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy Subjects
NCT03698513 ·Status: COMPLETED ·Phase: PHASE1
-
Assessment of Quitting Versus Using Aspirin Therapy In Patients Treated With Oral Anticoagulation for Atrial Fibrillation or Other Indication With Stabilized Coronary Artery Disease
NCT04217447 ·Status: TERMINATED ·Phase: PHASE3
-
The Middle East Dual Anti-platelet Treatment in Acute Transient Ischemic Attack
NCT02144831 ·Status: WITHDRAWN ·Phase: PHASE4
-
Clopidogrel With Aspirin in High-risk Patients With Acute Non-disabling Cerebrovascular Events II
NCT04078737 ·Status: COMPLETED ·Phase: PHASE3
-
Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI
NCT02640794 ·Status: COMPLETED ·Phase: PHASE4
-
Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)
NCT00249873 ·Status: COMPLETED ·Phase: PHASE3
-
Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE W)
NCT00243178 ·Status: TERMINATED ·Phase: PHASE3
-
Impact of Hybrid Coronary Revascularization on Antiplatelet Therapy
NCT02293928 ·Status: COMPLETED
-
Efficacy and Safety of Adding Clopidogrel to Aspirin or Use of Metoprolol in Myocardial Infarction
NCT00222573 ·Status: COMPLETED ·Phase: PHASE4
-
Cost Effectiveness Analysis In Patients With Heart Valve Prosthesis
NCT02022527 ·Status: UNKNOWN ·Phase: PHASE4
-
Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
NCT01924325 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Short Versus Long Antiplatelet Therapy After TAVI
NCT06518317 ·Status: RECRUITING ·Phase: PHASE3