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COmbining Oral Letrozole and Clomiphene for Ovarian Stimulation

NCT02288143 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2015-12-02

No results posted yet for this study

Summary

This is a pilot study evaluating the effect of a simplified low-cost (friendly) controlled ovarian stimulation using clomiphene citrate, letrozole, and low-dose hMG on the number of oocytes retrieved.

Conditions

Interventions

DRUG

COOL-COS

Controlled ovarian stimulation will start on the second or third day of a menstrual cycle: * Oral clomiphene citrate: 100 mg/day until the day of the triggering. * Oral letrozole: 7.5 mg/day during the first 5 days of the controlled ovarian stimulation. * hMG: 150 IU every other day beginning on the day 6 of the controlled ovarian stimulation. The triggering will be performed using urinary hCG (5,000 IU subcutaneous). * 1-2 days after the identification of one follicle ≥ 17 mm * 0-1 days after the identification of one follicle ≥ 19 mm.

Sponsors & Collaborators

  • University of Sao Paulo

    lead OTHER

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2015-03-31
Completion
2015-03-31

Countries

  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02288143 on ClinicalTrials.gov