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Efficacy of Oral Probiotic Administration in Patients With Chronic Periodontitis

NCT02283736 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2016-06-15

No results posted yet for this study

Summary

The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic tablets as an adjunct to scaling and root planning (SRP).

Material and methods: Thirty six chronic periodontitis patients will be recruited and monitored clinically, immunologically and microbiologically at baseline, 3 and 6 months after therapy. All patients will receive scaling and root planning and randomly will be assigned over an experimental (SRP + probiotic, n=18) or control (SRP + placebo, n=18) group. The tablets will be used once per day during 3 months.

Conditions

  • -Chronic Periodontitis

Interventions

OTHER

Lactobacillus rhamnosus SP1

Tablet containing Lactobacillus rhamnosus SP1

OTHER

Talc powder

Tablet containing talc powder

PROCEDURE

Periodontal treatment

Scaling and root planning

Sponsors & Collaborators

  • Jorge Gamonal

    lead OTHER

Principal Investigators

  • Jorge Gamonal, Professor · Faculty of Dentistry of University of Chile

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2015-06-30
Completion
2016-12-31

Countries

  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02283736 on ClinicalTrials.gov