Substudy : Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
NCT02282436 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2016-09-08
Summary
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Its prevalence is in progression and COPD is expected to become the fourth leading cause of death by 2030. COPD is characterized by periods of stability interspersed with acute infectious/inflammatory flare-ups, also called acute exacerbations, during which patients deteriorate, sometimes to the point of requiring immediate medical assistance. Although most patients eventually recover, repeated episodes of exacerbations may accelerate COPD progression. Exacerbations may further compromise the integrity of limb muscles by promoting further loss in muscle mass and strength.
The overall objective of this substudy is to elucidate how an acute COPD exacerbation may affect limb muscles.
Conditions
Interventions
- OTHER
-
No specific intervention for this study
No specific intervention for this study
Sponsors & Collaborators
-
Canadian Institutes of Health Research (CIHR)
collaborator OTHER_GOV -
Laval University
lead OTHER
Principal Investigators
-
François Maltais, MD, PhD · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Eligibility
- Min Age
- 50 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-05-31
- Primary Completion
- 2017-05-31
- Completion
- 2018-05-31
Countries
- Canada
Study Locations
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