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The Role of Narrowband Ultraviolet B Exposure in the Maintenance of Vitamin D Levels During Winter

NCT02275650 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 37

Last updated 2014-10-27

No results posted yet for this study

Summary

The investigators investigated the ability of narrowband ultraviolet B (nbUVB) treatment in the maintenance of vitamin D levels achieved during the summer in Finland. The investigators randomized 37 subjects into groups of 17 and 18 subjects. The other group received 2 standard erythema doses (SED) nbUVB exposure every other week until week 24, and serum 25(OH)D levels were measured at the onset and at weeks 6, 14, 20, 26 and 30. The control group was not illuminated and serum samples were analyzed correspondingly. Punch biopsies were taken at the onset and at week 14 for CYP27A1 and CYP27B1 enzyme expression level analyses.

Conditions

  • Vitamin D Deficiency

Interventions

RADIATION

nbUVB

2 SED nbUVB exposure will be given every other week

Sponsors & Collaborators

  • Tampere University Hospital

    collaborator OTHER

  • Joint Authority for Päijät-Häme Social and Health Care

    lead OTHER

Principal Investigators

  • Toni T Karppinen, MD · Päijät Häme Central Hospital

  • Erna Snellman, professor · Tampere University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-09-30
Primary Completion
2014-05-31
Completion
2014-05-31

Countries

  • Finland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02275650 on ClinicalTrials.gov