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Progesterone Amplifies Estrogen-stimulated Growth Hormone Secretion in Older Women

NCT02272647 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 47

Last updated 2018-03-22

No results posted yet for this study

Summary

Progesterone amplifies estrogen-stimulated Growth Hormone (GH) secretion in postmenopausal women. Preliminary data are sought to estimate statistical power for more detailed studies of this hypothesis.

Conditions

  • Healthy

Interventions

DRUG

IM Saline Placebo (0.25 ml)

DRUG

IM Estradiol valerate (2.5 mg)

DRUG

IM Saline Placebo (0.5 ml)

DRUG

IM Estradiol valerate (5.0 mg)

DRUG

Oral Micronized Progesterone

DRUG

Oral Placebo

DRUG

Ghrelin (0.3 ug/kg)

DRUG

Medroxyprogesterone - Acetate

DRUG

Oral Placebo

(in lieu of Medroxyprogesterone)

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
50 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-12-31
Primary Completion
2016-12-31
Completion
2018-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02272647 on ClinicalTrials.gov