Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal Varices

Summary

Aim of this thesis is to predict the incidence of esophageal ulcer bleeding after endoscopic management of esophageal varices.

This study will be in the department of Tropical Medicine and Infectious Diseases, Tanta University, in at least six months in the period from august 2014 to march 2015 or until the target number of patients reached whichever is longer.

Conditions

• Esophageal and Gastric Varices
• Ulcer
• Cirrhosis
• Hypertension, Portal

Interventions

DEVICE

Esophagogastroduodenoscope

Endoscopic therapies for varices aim to reduce variceal wall tension by obliteration of the varix. The two principal methods available for esophageal varices are endoscopic sclerotherapy (EST) and band ligation (EBL). Endoscopic therapy is a local treatment that has no effect on the pathophysiological mechanisms that lead to portal hypertension and variceal rupture. However, a spontaneous decrease in HVPG occurs in around 30% of patients treated with either EST or EBL to prevent variceal rebleeding.

Sponsors & Collaborators

• Tanta University

  lead OTHER

Principal Investigators

• Asem A Elfert, MD · Tanta Faculty of Medicine, Professor

• Fat-heya E Assel, MD' · Tanta Faculty of Medicine, Professor

• Ferial Elkalla, MD · Tanta Faculty of Medicine, Professor

• Galal Elkassas, MD · Tanta Faculty of Medicine, Professor

• Mohamed Elhendawy · Dr.

• Loai Mansour · Dr.

• Mohamed Rabei · Dr.

• Samah Mosaad · Dr.

• Ibrahim A Kabbash, MD · Tanta Faculty of Medicine, Professor

• Mohamed Elkassas · Dr.

• Islam S Ismail · Dr.

• Ibrahim Shebl · Dr.

Study Design

Allocation

NA

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-08-31

Primary Completion

2015-03-31

Completion

2015-03-31

Countries

• Egypt

Study Locations