Electrical Stimulation of the Paretic Upper Limb in the Early Stroke Phase

Summary

This study evaluates the effect of electrical somatosensory stimulation (ESS) on the restoration of upper limb functioning in acute stroke patients. The effect will be measured at the end of the intervention and six months post-stroke. We expect that ESS facilitates the restoration of upper limb functioning and the brain reorganization following stroke.

Conditions

• Stroke, Acute

Interventions

OTHER

Continuous, suprasensory ESS

1 hour of ESS daily from Monday to Sunday during hospitalization, but no longer than 4th week post-stroke. The ESS will be applied immediately prior to OT/PT training which will include 15 minutes of repetitive, task-oriented upper limb training during the first 30 minutes after cessation of ESS.

OTHER

Intermittent, suprasensory ESS

1 hour of ESS daily from Monday to Sunday during hospitalization, but no longer than 4th week post-stroke. The ESS will be applied immediately prior to OT/PT training which will include 15 minutes of repetitive, task-oriented upper limb training during the first 30 minutes after cessation of ESS.

Sponsors & Collaborators

• Bispebjerg Hospital

  collaborator OTHER

• Region Capital Denmark

  collaborator OTHER

• Lundbeck Foundation

  collaborator OTHER

• Bevica Fonden

  collaborator OTHER

• Manager Jacob Madsen and his wife, Olga Madsen's Foundation

  collaborator UNKNOWN

• Danish Association of Occupational Therapist

  collaborator OTHER

• University of Copenhagen

  lead OTHER

Principal Investigators

• Peter Magnusson, D.Sc · Musculoskeletal Rehabilitation Research Unit and Institute of Sports Medicine, Bispebjerg Hospital & University of Copenhagen

• Emma Ghaziani, PhD stud · Musculoskeletal Rehabilitation Research Unit, Bispebjerg Hospital & University of Copenhagen

• Christian Couppé, PhD · Musculoskeletal Rehabilitation Research Unit and Institute of Sports Medicine, Bispebjerg Hospital & University of Copenhagen

• Hanne Christensen, MD, PhD · Bispebjerg Hospital & University of Copenhagen

• Volkert Siersma, statistician · Research Unit Of General Practice, Copenhagen

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-13

Primary Completion

2017-08-10

Completion

2017-08-10

Countries

• Denmark

Study Locations