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Aprepitant to Mitigate Opioids' Cognitive Side Effects

NCT02226601 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2015-06-02

No results posted yet for this study

Summary

Morphine and similar substances (called opioids) are often prescribed for moderate to severe pain, such as after a surgery, thus allowing for minimal pain and a better recovery. Unfortunately various, non-dangerous side effects from opioids occur often that limit the way patients feel and can take of themselves, despite otherwise good pain control and minimal limitations from the surgery itself.

Conditions

  • Cognitive Dysfunction

Interventions

DRUG

Aprepitant

3 days perioperative Aprepitant once a day

DRUG

Placebo

3 days perioperative Placebot once a day

Sponsors & Collaborators

  • University of Arizona

    lead OTHER

Principal Investigators

  • Kai Schoenhage, MD · University of Arizona

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2016-10-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02226601 on ClinicalTrials.gov