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Evaluation of the High Dose Vitamin D3 Supplementation Effect and Influence of Polymorphism VDR Gene on Oxidative Stress and Inflammatory Process in Elderly

NCT02222649 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2015-03-06

No results posted yet for this study

Summary

A vitamin D3 high dose would act as an antioxidant and anti-inflammatory improving markers of oxidative stress and inflammation in the elderly. Seniors exhibiting polymorphism in the VDR gene would become non-responsive to supplementation.

Conditions

  • Disorder of Aging

Interventions

DIETARY_SUPPLEMENT

Vitamin D3

High dose of 200,000 IU of cholecalciferol orally in a single dose

DIETARY_SUPPLEMENT

Placebo

Capsules of starch, no therapeutic action

Sponsors & Collaborators

  • Federal University of Paraíba

    lead OTHER

Principal Investigators

  • Isa Gabriela M Cavalcante, DDS · Federal University of Paraíba

  • Maria da Conceição R Gonçalves, PDH · Federal University of Paraíba

  • Alexandre S Silva, PHD · Federal University of Paraíba

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
90 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-07-31
Primary Completion
2015-05-31
Completion
2015-09-30

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02222649 on ClinicalTrials.gov