Apoe Impact Study on Brain Structure and Function, in a Population 45 to 75 Years Old
NCT02198586 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 575
Last updated 2017-03-03
Summary
The purpose of this study is to investigate the influence of the APOE genotype on brain morphology, function and metabolism, related to other factors such as cognitive reserve, cognition and episodic memory, in subjects at greater risk of developing AD.
Conditions
Sponsors & Collaborators
-
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
lead OTHER
Principal Investigators
-
Juan D Gispert, PhD · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
-
José L Molinuevo, MD, PhD · IDIBAPS, Hospital Clinic de Barcelona, Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Eligibility
- Min Age
- 45 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-04-30
- Primary Completion
- 2015-07-31
- Completion
- 2015-09-30
Countries
- Spain
Study Locations
More Related Trials
-
Prospective Memory Imaging
NCT01638884 ·Status: UNKNOWN ·Phase: NA
-
Early Diagnosis of Alzheimer's Disease: Clinical, Neuropsychological and Neuroimaging Follow-up of a Cohort of Patients With an Isolated Memory Impairment
NCT00684281 ·Status: COMPLETED ·Phase: NA
-
Technical Development of Multi-Parametric Renocerebral MRI
NCT02831335 ·Status: RECRUITING
-
FluoroAv45 Imaging Research-in Alzheimer's Disease
NCT01325259 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Positron Emission Tomography (PET) Imaging With MNI-558
NCT01217021 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
NCT07099053 ·Status: RECRUITING
-
New Biomarker for Alzheimer's Disease Diagnostic
NCT01315639 ·Status: COMPLETED ·Phase: NA
-
Cerebral Substrates of Prospective Memory in Young and Its Disruption in Normal Aging and in Alzheimer's Disease: A Study in Anatomical MRI, Diffusion Tensor MRI and Functional MRI
NCT02522091 ·Status: UNKNOWN ·Phase: NA
-
Relationship Between Protein Biomarkers in Cerebrospinal Fluid and Alzheimer&Apos;s Disease in Patients With Depression
NCT02303158 ·Status: TERMINATED
-
Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults
NCT03129269 ·Status: COMPLETED ·Phase: NA
-
Determinants of Cognitive Impairment After Acute Coronary Syndrome
NCT00982176 ·Status: COMPLETED
-
Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation
NCT01925196 ·Status: COMPLETED
-
Cognitive, Morphological and Neurobiological Progressive Aspects in Bipolar Disorders in the Elderly: Toward to a Neurodegenerescence Detection?
NCT02843906 ·Status: UNKNOWN ·Phase: NA
-
Brain-heart Interaction in Coronary Plaque Stability and Cardiovascular Events
NCT05545618 ·Status: UNKNOWN
-
Identification of Biomarkers Sensitive to Disease Progression in Patients With Mild Cognitive Impairment
NCT01425957 ·Status: COMPLETED ·Phase: NA
-
Biomarkers of Cognitive Impairment in Blood Cells
NCT05582941 ·Status: COMPLETED
-
Intracranial Aneurysms and Cognitive Function
NCT01320306 ·Status: TERMINATED
-
Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
NCT06561906 ·Status: RECRUITING
-
Cohort Study on the Effects of Aging in Acquired Brain Injury Patients
NCT05499806 ·Status: UNKNOWN
-
Apolipoprotein E Gene and Functional MRI
NCT01287819 ·Status: COMPLETED
-
Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
NCT07314190 ·Status: ENROLLING_BY_INVITATION
-
Characterization of Cerebral Tau Aggregates With 18F-RO6958948 PET in the ALFA Population
NCT04482660 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Neuro Imaging and Multimodal Alzheimer's Disease
NCT02839187 ·Status: COMPLETED ·Phase: NA
-
Molecular PET Imaging and Plasma Biomarkers in Alzheimer´s Disease and Other Neurodegenerative Diseases
NCT06731842 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Amyloid-β Clearance Mechanisms in Alzheimer's Disease
NCT05059158 ·Status: RECRUITING