Tofacitnib for the Treatment of Alopecia Areata and Variants
NCT02197455 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2017-04-04
Summary
The purpose of this study is to investigate the ability of tofacitinib citrate, a Janus kinase inhibitor, to generate hair regrowth in patients with moderate to severe alopecia areata and its variants.
Conditions
- Alopecia Areata (AA)
- Alopecia Totalis (AT)
- Alopecia Universalis (AU)
Interventions
- DRUG
-
Tofacitinib Administration
5 mg of Tofacitinib will be taken by mouth twice daily for 3 months.
Sponsors & Collaborators
-
Yale University
lead OTHER
Principal Investigators
-
Brett King, MD · Yale University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-07-31
- Primary Completion
- 2015-07-31
- Completion
- 2015-07-31
Countries
- United States
Study Locations
More Related Trials
-
Pilot Study to Evaluate the Efficacy of Ruxolitinib in Alopecia Areata
NCT01950780 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Alopecia Areata (AA) With Dupilumab in Patients With and Without Atopic Dermatitis (AD)
NCT03359356 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Secukinumab for the Treatment of Alopecia Areata
NCT02599129 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia Areata
NCT05556265 ·Status: TERMINATED ·Phase: PHASE2
-
A Clinical Trial to Evaluate the Efficacy of Abatacept in Moderate to Severe Alopecia Areata
NCT01917058 ·Status: WITHDRAWN ·Phase: PHASE2
-
Efalizumab in the Treatment of Alopecia, Phase II
NCT00746980 ·Status: WITHDRAWN ·Phase: PHASE2
-
Abatacept Costimulatory Blockade in the Treatment of Alopecia Totalis/Universalis
NCT01314495 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study With Ruxolitinib Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)
NCT02553330 ·Status: TERMINATED ·Phase: PHASE2
-
Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot Study
NCT06202560 ·Status: COMPLETED ·Phase: NA
-
Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Universalis (AU) and Alopecia Totalis (AT)
NCT03315689 ·Status: COMPLETED ·Phase: PHASE2
-
Dupilumab in the Treatment of Pediatric Alopecia Areata
NCT05866562 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
NCT07029711 ·Status: RECRUITING ·Phase: PHASE3
-
An Open-Label Single-Arm Clinical Trial to Evaluate The Efficacy of Abatacept in Moderate to Severe Patch Type Alopecia Areata
NCT02018042 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Oral Tofacitinib in the Treatment of Alopecia Areata
NCT06157905 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE Study
NCT06573593 ·Status: RECRUITING
-
A Study in Male and Female Subjects With Androgenetic Alopecia Treated With ATI-50002 Topical Solution
NCT03495817 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Application of Stem Cell Educator Therapy in Alopecia Areata
NCT04011748 ·Status: UNKNOWN ·Phase: PHASE2
-
A Pilot Study of Tralokinumab in Subjects With Moderate to Severe Alopecia Areata
NCT02684097 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata
NCT06012240 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata
NCT03354637 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Tolerability Study of Two Dosing Regimens of CTP-543 in Adults With Alopecia Areata
NCT03941548 ·Status: COMPLETED ·Phase: PHASE2
-
Regeneron AA Multicenter (Dupilumab)
NCT05551793 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of Age
NCT05650333 ·Status: COMPLETED ·Phase: PHASE1
-
Pilot Study of the Safety and Efficacy of Apremilast in Subjects With Moderate to Severe Alopecia Areata
NCT02684123 ·Status: COMPLETED ·Phase: NA
-
Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata
NCT02974868 ·Status: COMPLETED ·Phase: PHASE2