Endogenous Opioid Mechanisms for Rejection Sensitivity
NCT02189785 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 114
Last updated 2020-10-22
Summary
This project hypothesizes that the brain's opioid system determines rejection sensitivity, a personality trait that is a vulnerability factor and feature of several psychiatric disorders. This project will use positron emission tomography to measure the brain's opioid response to social rejection and acceptance in a nonclinical population with varying levels of rejection sensitivity. The results will provide the first major step towards understanding a neurotransmitter mechanism for rejection sensitivity, allowing for further investigation into predicting and treating its associated disorders.
Conditions
- Rejection Sensitivity
Sponsors & Collaborators
- collaborator OTHER
-
National Institute of Mental Health (NIMH)
collaborator NIH - lead OTHER
Principal Investigators
-
David T Hsu, Ph.D. · Stony Brook University
Eligibility
- Min Age
- 18 Years
- Max Age
- 25 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-08-31
- Primary Completion
- 2019-06-06
- Completion
- 2019-06-06
Countries
- United States
Study Locations
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