Intensive Smoking and Alcohol Cessation Intervention in Bladder Cancer Surgery Patients

Summary

Radical cystectomy provides the best cancer-specific survival for muscle-invasive urothelial cancer. However the postoperative morbidity remains at 11-68 %. Smoking and alcohol consumption above two drinks per day is associated with an increased risk of postoperative morbidity. Six-eight weeks of smoking and alcohol abstinence prior to elective surgery is recommended to reduce this risk, but for cancer patients the preoperative period is often very short. This randomised clinical trial (STOP-OP) will reach a conclusion on the effect of a new Gold Standard Programme for both smoking and alcohol cessation Intervention using the Gold Standard Programme (GSP) on the frequency and severity of postoperative complications after bladder cancer surgery.

Conditions

• Bladder Cancer
• Smoking
• Alcohol Consumption

Interventions

BEHAVIORAL

Educational programme for smoking and alcohol cessation

5 meetings within 6 weeks containing education and pharmacologic support

Sponsors & Collaborators

• Frederiksberg University Hospital

  collaborator OTHER

• Aalborg University Hospital

  collaborator OTHER

• Copenhagen University Hospital at Herlev

  collaborator OTHER

• Odense University Hospital

  collaborator OTHER

• Aarhus University Hospital

  collaborator OTHER

• Karolinska Institutet

  collaborator OTHER

• Rigshospitalet, Denmark

  lead OTHER

Principal Investigators

• Hanne Tønnesen, Professor · WHO-CC, Clinical Health Promotion Centre, Bispebjerg/Frederiksberg University Hospital, DK 2000 Frederiksberg, Denmark

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

100 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-11-30

Primary Completion

2018-07-31

Completion

2018-07-31

Countries

• Denmark

Study Locations