Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI)
NCT02181985 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 5989
Last updated 2014-07-14
Summary
The objective of ASSENT 3 was to evaluate the safety and efficacy of full dose tenecteplase with heparin sodium (group A), full dose tenecteplase combined with enoxaparin (group B) and half dose tenecteplase combined with abciximab and heparin sodium (group C).
Conditions
Interventions
- DRUG
-
Full dose TNK-tPA
- DRUG
-
Half dose TNK-tPA
- DRUG
-
Heparin
- DRUG
-
Enoxaparin
- DRUG
-
Abciximab
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-05-31
- Primary Completion
- 2001-04-30
More Related Trials
-
Anti-thrombotic Monotherapy With the HeartMate 3 LVAS
NCT03704220 ·Status: UNKNOWN ·Phase: NA
-
Secondary Prevention of Venous Thrombo Embolism (VTE).
NCT00329238 ·Status: COMPLETED ·Phase: PHASE3
-
Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism
NCT02585713 ·Status: COMPLETED ·Phase: PHASE3
-
LV Thrombus Pilot Study for Comparing Enoxaparin Vs. Warfarin
NCT00321009 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Dabigatran Compared to Warfarin for 6 Month Treatment of Acute Symptomatic Venous Thromboembolism
NCT00291330 ·Status: COMPLETED ·Phase: PHASE3
-
Bioequipotency Study of Idrabiotaparinux and Idraparinux in Patients With Deep Venous Thrombosis of the Lower Limbs
NCT00311090 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness
NCT00457002 ·Status: COMPLETED ·Phase: PHASE3
-
Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE)
NCT00680186 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Venous Thromboembolism Prevention in High-Risk Trauma Patients
NCT02412982 ·Status: COMPLETED ·Phase: PHASE4
-
Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis
NCT00790335 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach
NCT00345618 ·Status: COMPLETED ·Phase: PHASE3
-
Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement
NCT03284827 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety Study of Apixaban for Extended Treatment of Deep Vein Thrombosis or Pulmonary Embolism
NCT00633893 ·Status: COMPLETED ·Phase: PHASE3
-
ABRIDGE: Low Molecular Weight Heparin in Bridging Patients After Mechanical Valve Replacement
NCT00298285 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery
NCT03251482 ·Status: COMPLETED ·Phase: PHASE2
-
The Comparative Safety and Effectiveness of Dabigatran, Versus Rivaroxaban, and Apixaban Utilized in the Department of Defense Non-Valvular Atrial Fibrillation Patient Population: A Retrospective Database Analysis
NCT03026556 ·Status: COMPLETED
-
Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy
NCT06904911 ·Status: RECRUITING ·Phase: PHASE2
-
Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE(Venous Thromboembolism)
NCT02064439 ·Status: COMPLETED ·Phase: PHASE3
-
RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding
NCT02829957 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests (Module 1 of 4)
NCT01758432 ·Status: COMPLETED ·Phase: PHASE2
-
Apixaban in Thrombocytopenia
NCT06886516 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)
NCT02164864 ·Status: COMPLETED ·Phase: PHASE3
-
Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement
NCT00152971 ·Status: COMPLETED ·Phase: PHASE3
-
Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Hip Replacement Surgery (ADVANCE-3)
NCT00423319 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Apixaban for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery
NCT00371683 ·Status: COMPLETED ·Phase: PHASE3