Apixaban in Thrombocytopenia
NCT06886516 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-04-15
Summary
This study is being done to determine the feasibility and safety of using a novel dose adjusted apixaban for the management of participants with cancer-associated venous thromboembolism (blood clot) or and thrombocytopenia (low number of platelets in the blood). Investigators are also looking to see if participants on this treatment have fewer bleeding episodes.
The name of the study drug involved in this study is:
-Apixiban (a type of anticoagulant)
Conditions
- Deep Vein Thrombosis
- Pulmonary Embolism and Thrombosis
- Thrombocytopenia
- Recurrent Venous Thromboembolism
Interventions
- DRUG
-
Apixaban
A factor Xa inhibitor, 2.5 and 5 mg tablets, by mouth per protocol.
Sponsors & Collaborators
-
Rushad Patell
lead OTHER
Principal Investigators
-
Rushad Patell, MD · Beth Israel Deaconess Medical Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-28
- Primary Completion
- 2027-07-01
- Completion
- 2029-07-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Study of Apixaban for the Prevention of Thrombosis-related Events in Patients With Acute Medical Illness
NCT00457002 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism
NCT00643201 ·Status: COMPLETED ·Phase: PHASE3
-
Apixaban for Secondary Prevention of Thromboembolism Among Patients With AntiphosPholipid Syndrome
NCT02295475 ·Status: COMPLETED ·Phase: PHASE4
-
Reduced-Dose Apixaban and Rivaroxaban Versus Low-Molecular-Weight Heparin in Patients With Hematologic Malignancies
NCT07270263 ·Status: RECRUITING ·Phase: NA
-
A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects
NCT02074358 ·Status: COMPLETED ·Phase: PHASE1
-
API-CAT STUDY for APIxaban Cancer Associated Thrombosis
NCT03692065 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Apixaban in Malignancy With Deep Venous Thrombosis
NCT04462003 ·Status: UNKNOWN ·Phase: PHASE3
-
Apixaban for the Treatment of Venous Thromboembolism in Patients With Cancer
NCT03045406 ·Status: COMPLETED ·Phase: PHASE3
-
DOAC - Dosing Options in AntiCoagulation Prophylaxis
NCT07005024 ·Status: RECRUITING ·Phase: PHASE3
-
AStudy To Evaluate Safety And Eficacy Of Apixaban In Japanese Acute Deep Vein Thrombosis (DVT) And Pulmonary Embolism (PE) Patients
NCT01780987 ·Status: COMPLETED ·Phase: PHASE3
-
Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients
NCT04243122 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2 Study To Evaluate The Safety Of Apixaban In Atrial Fibrillation
NCT00787150 ·Status: COMPLETED ·Phase: PHASE2
-
Anti-Platelet and Statin Therapy to Prevent Cancer-Associated Thrombosis
NCT02285738 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms
NCT05198960 ·Status: RECRUITING ·Phase: PHASE3
-
Optimal Duration of Anticoagulation Therapy for Isolated Distal Deep Vein Thrombosis in Patients With Cancer Study
NCT03895502 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Compare Health Care Costs Between Apixaban and Low Molecular Weight Heparin in Patients With Venous Thromboembolism and Cancer
NCT05643885 ·Status: COMPLETED
-
Apixaban as Treatment of Venous Thrombosis in Patients With Cancer: The CAP Study
NCT02581176 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
NCT05171049 ·Status: TERMINATED ·Phase: PHASE3
-
Reversibility of Apixaban Anticoagulation With the Four Factor Prothrombin Complex Concentrate Kcentra
NCT02270918 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.
NCT04229264 ·Status: UNKNOWN ·Phase: PHASE3
-
Pharmacokinetics Study Of Rivaroxaban and Apixaban in Cancer Patients
NCT05819736 ·Status: UNKNOWN
-
Comparison of the Effects of Apixaban on Thrombin Generation in Patients With de Novo Multiple Myeloma
NCT06474182 ·Status: RECRUITING ·Phase: NA
-
Apixaban For Thromboprophylaxis In Patients With Acute Spinal Cord Injury
NCT03200613 ·Status: TERMINATED ·Phase: PHASE2
-
Apixaban Versus Warfarin in the Evaluation of Progression of Atherosclerotic Calcification and Vulnerable Plaque
NCT02090075 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Gather Information How Often Venous Thromboembolism Occurs in Prostate Cancer Patients in Sweden and How This Condition is Treated With Blood Thinners
NCT03965741 ·Status: COMPLETED