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Serial Daily Diaphragm Ultrasounds in Ventilated Patients

NCT02174029 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 61

Last updated 2015-03-11

No results posted yet for this study

Summary

When a person is put on a breathing machine the investigators think that the breathing muscles can get weaker. The investigators are not sure how quickly this happens but in some people this leads to problems when they try to breathe on their own without the breathing machine. The diaphragm is at the bottom of a person's chest separating their lungs from what is in their belly and it is a very strong muscle. In fact, it is main muscle that one uses for breathing.

An ultrasound machine is a painless way to see what is happening beneath the skin. It is safe and easy to do. Using an ultrasound the investigators are planning to measure how thick the diaphragm is and how much it changes while a person is on a breathing machine in the ICU.

Getting a better understanding of this condition could lead to improved treatments that might help support patients who require a ventilator for breathing.

The investigators hypothesis is that patients for whom the breathing machine is doing all of the work of breathing, will have their diaphragm thickness gradually decrease and changing to a breathing modem mode where they have to put in more effort the diaphragm thickness will start increasing again.

Conditions

  • Muscle Atrophy or Weakness
  • Ventilator-associated Lung Injury

Interventions

PROCEDURE

Ventilation- mandatory

Patient days during which only a mandatory ventilation mode was used and prior to this no voluntary mode was used.

PROCEDURE

Ventilation- voluntary mode only

Patient days on a voluntary mode with no preceding days with a majority of time spend on a mandatory mode

PROCEDURE

Voluntary with preceding mandatory

Patient days on a voluntary vent mode with at least one day prior during which the majority of the vent mode was mandatory.

Sponsors & Collaborators

  • Fraser Health

    collaborator OTHER

  • Steve Reynolds

    lead OTHER

Principal Investigators

  • Steven Reynolds, MD · Royal Columbian Hospital, Fraser Health

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2014-08-31
Completion
2014-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02174029 on ClinicalTrials.gov