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Cortical Excitability Using Robotised and Neuronavigated Transcranial Magnetic Stimulation

NCT02168413 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 144

Last updated 2021-12-08

No results posted yet for this study

Summary

This study has two main goals :

* to develop the cortcial excitbality (CE) measurement methodology using coupling between transcranial magnetic stimulation (TMS) and physiological recordings such as electroencephalography (EEG) and electromyography (EMG),
* to automatize these measurements using robotized TMS.

Assessing CE is a preliminary and crucial step in any TMS protocol, in either fundamental or clinical research. It is an important indicator which determine the stimulation power applied on the cortical target during the TMS experiment, or during the rTMS cure (patients). CE is in general measured on the motor cortex using EMG activity as the main indicator of the system's response, whatever the real cortical target is located. The present study thus propose to generalize this measurement on other cortical areas in link with the actual targets, and using other external recordings such as EEG. Moreover, as neuronavigation systems significantly improved TMS precision in the past years, CE measurements could significantly gain to become fully automatized using robotized TMS.

Conditions

  • Cortical Excitability
  • Robotized TMS

Sponsors & Collaborators

  • Centre National de la Recherche Scientifique, France

    collaborator OTHER

  • University Hospital, Grenoble

    lead OTHER

Principal Investigators

  • Thierry BOUGEROL, PUPH · University Hospital, Grenoble

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-05-14
Primary Completion
2021-05-12
Completion
2021-05-12

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02168413 on ClinicalTrials.gov