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Role of SNP and DIGOXIN Response in Atrial Fibrillation Patients

NCT02167165 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2020-02-12

No results posted yet for this study

Summary

This study tested the hypothesis that response to digoxin is modulated by single Nucleotid Polymorphism (SNP):

* Multi Drug Resistance (MDR1) gene haplotypes and Solute carrier organic anion transporter family member 1B3 (SLCO1B3) gene Polymorphism and their role in the response to treatement.
* Aldosterone synthase (CYP11B2) gene and sodium channel, voltage-gated, type V alpha subunit gene (SCN5A) correlated with atrial fibrillation and their roles in response to digoxin.

Conditions

Interventions

DRUG

Digoxin Injection

Patients consulting the ED for Acute onset AF received 0.5 mg digoxin by oral root

Sponsors & Collaborators

  • University of Monastir

    lead OTHER

Principal Investigators

  • Nouira Samir, Professor · University of Monastir

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2016-12-31
Completion
2016-12-31

Countries

  • Tunisia

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02167165 on ClinicalTrials.gov