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Cognitive Rehabilitation for Gulf War Illness

NCT02161133 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 268

Last updated 2020-08-26

Study results available
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Summary

There are almost 700,000 Gulf War Veterans (GWV) with 25-30% suffering from a devastating multi-symptom illness coined Gulf War Illness (GWI). GWV with GWI report significant activity limitations and chronic cognitive problems consistent with problem-solving deficits. Problem-solving is considered the most complex of cognitive abilities and is what enables us to conduct complicated behaviors such as setting goals, sequencing and multi-tasking. As a result studies have found that problem-solving deficits are prospectively related to a greater risk of disability. Despite published reports documenting these problems there are no treatments that target the problem-solving deficits of GWI. This proposal seeks to determine whether Problem-Solving Therapy, a patient centered cognitive rehabilitation therapy, can reduce disability by compensating for problem-solving deficits.

Conditions

  • Gulf War Illness

Interventions

BEHAVIORAL

Problem-Solving Therapy

Problem-Solving Therapy is a treatment approach that teaches patients strategies to address real-life problems.

BEHAVIORAL

Health Education

Health Education provides didactic information about Gulf War Illness

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Lisa M McAndrew, PhD · East Orange Campus of the VA New Jersey Health Care System, East Orange, NJ

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2018-12-31
Completion
2019-09-01

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02161133 on ClinicalTrials.gov