MedTrace Logo

Quantitative Measurement and Correlates of the Latent HIV Reservoir in Virally Suppressed Ugandans

NCT02154035 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2026-05-01

No results posted yet for this study

Summary

Background:

Human Immunodeficiency Virus (HIV) is the virus that causes AIDS. HIV can hide in the blood for many years, even in people who have their HIV infection under control. HIV that is hiding in the blood is called the "latent HIV reservoir." Researchers want to find out more about it in this study. This knowledge may help them develop new ways to prevent or control HIV. This study will draw its participants from the Rakai Health Sciences Program in rural southwestern Uganda.

Objective:

\- To measure and learn about the latent HIV reservoir in Ugandans with HIV.

Eligibility:

\- Men and women at least 18 years of age with HIV.

Design:

* Participants will have a medical history and physical exam. Their medical records will be reviewed. Researchers will ask participants about their health and recent illnesses. Participants able to get pregnant will have their urine tested for pregnancy.
* Participants will have their finger pricked to see if they have enough red blood cells to be eligible for the study.
* If eligible, participants will have blood drawn through a needle in the arm. Their blood will also be tested for other diseases.
* After the blood draw, participants will be asked to stay seated or lying down if they are not feeling well for up to 30 minutes.

Conditions

Sponsors & Collaborators

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    collaborator NIH

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • National Institute of Allergy and Infectious Diseases (NIAID)

    lead NIH

Principal Investigators

  • Steven J Reynolds, M.D. · National Institute of Allergy and Infectious Diseases (NIAID)

Eligibility

Min Age
18 Years
Max Age
49 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-05-31
Primary Completion
2021-11-26
Completion
2021-11-26

Countries

  • Uganda

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02154035 on ClinicalTrials.gov