A Study of Pioglitazone and Carboplatin in Patients With Advanced Solid Tumors
NCT02133625 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 14
Last updated 2026-03-30
Summary
The proposed investigation is a Phase 1 trial to determine the safety, tolerability, and maximum tolerated dose (MTD) of the combination of pioglitazone ( and carboplatin patients with advanced or metastatic solid malignancies.
Conditions
- Advanced Solid Tumor
- Metastatic Solid Tumor
Interventions
- DRUG
- DRUG
-
pioglitazone
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
James Cleary, MD, PhD · Dana Farber Cancer Instiute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-08-31
- Primary Completion
- 2016-03-31
- Completion
- 2026-01-31
Countries
- United States
Study Locations
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