Study on the microRNA Expression Level in Postmenopausal Osteoporosis
NCT02128009 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2019-02-26
Summary
The miRNA plays an important regulation role in gene expression, and also closely related to bone metabolism. Previous research found that postmenopausal osteoporosis with kidney Yin deficiency syndrome (POP) is associated with CLCF1 gene. This project proposed by bioinformatics prediction CLCF1 targeted regulation of miRNAs, and use the 3 'UTR dual luciferase report system for target validation, aimed at the miRNA levels to explore postmenopausal osteoporosis molecular mechanism with kidney Yin deficiency syndrome.
Conditions
- Postmenopausal Osteoporosis
Interventions
- OTHER
-
osteoporosis
Sponsors & Collaborators
-
Fujian Academy of Traditional Chinese Medicine
lead OTHER
Principal Investigators
-
FJ ITCM, provincial · Fujian Institute of Trational Chiness Medicine
Eligibility
- Min Age
- 45 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-02-28
- Primary Completion
- 2016-12-31
- Completion
- 2017-01-31
Countries
- China
Study Locations
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