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The Type of Hepatoglobin in IUGR

NCT02127385 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2014-04-30

No results posted yet for this study

Summary

Intra Uterine Growth Restriction is associated with increased oxidative stress. Haptoglobin (Hp) is an abundant plasma glycoprotein produced in the liver. The function of Hp is as anti oxidant agent, it binds free hemoglobin (Hb) released from red blood cells to decrease oxidative tissue damage. There are 3 differenet genotype of haptoglobin Hp 1-1 Hp 1-2 and Hp 2-2 with different anti oxidant properties and different prevalence ( Hp 1-1, Hp 1-2 and Hp 2-2approximately 16%, 48% and 36% respectively) . we hypotheise that IUGR will be more common and severe in the Hp 2-2 genotype with the less anti oxidant properties.

Conditions

  • Haptoglobin Type

Sponsors & Collaborators

  • Hillel Yaffe Medical Center

    lead OTHER_GOV

Principal Investigators

  • RON BELOOSESKY, M.D · HILLEL YAFFE MEDICAL CENTER- TECHNION

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2015-04-30

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View NCT02127385 on ClinicalTrials.gov