Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96
NCT02122822 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2017-11-17
Summary
RATIONALE: heat shock protein gp96-peptide complex made from a person's tumor cells may help the body build an effective immune response to kill tumor cells.
PURPOSE: This trial is studying the safety and effectiveness of autologous gp96 treatment of glioblastoma and to see how well it works in treating patients with newly diagnosed supratentoria glioma.
Conditions
Interventions
- BIOLOGICAL
-
gp96
vaccination of autologous gp96 derived from tumor tissue + basal treatment
Sponsors & Collaborators
-
Beijing Tiantan Hospital
collaborator OTHER -
Cure&Sure Biotech Co., LTD
lead INDUSTRY
Principal Investigators
-
Zhixian Gao, Doctor · Beijing Tiantan Hospital
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-07-31
- Primary Completion
- 2015-07-31
- Completion
- 2017-05-31
Countries
- China
Study Locations
More Related Trials
-
Immunotoxin Therapy in Treating Patients With Malignant Glioma
NCT00006268 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Safety Study of Autologous TILs Therapy for Patients With Glioblastoma Multiforme.
NCT05333588 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT01222221 ·Status: COMPLETED ·Phase: PHASE1
-
IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma
NCT05353530 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
WL276 CAR-T Cell Therapy for CD276 Positive Recurrent or Progressive Glioblastoma Patients
NCT06691308 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
The Safety and Efficacy of SNC-109 CAR-T Cells Therapy the Recurrent Glioblastoma
NCT05868083 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma
NCT01081223 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of GC101 TIL in Brain Glioma (Soochow2)
NCT04943913 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.
NCT04388033 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Nimotuzumab Plus Radiotherapy With Concomitant and Adjuvant Temozolomide for Cerebral Glioblastoma
NCT03388372 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Clinical Trial of a mRNA Vaccine for Recurrent or Progressive High-grade Glioma
NCT07306299 ·Status: RECRUITING ·Phase: PHASE1
-
BC008-1A Injection for Recurrent CNS WHO G4 Glioma
NCT06773481 ·Status: RECRUITING ·Phase: PHASE1
-
Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma
NCT01250470 ·Status: COMPLETED ·Phase: PHASE1
-
Personalized Vaccine for Patients With Recurrent Malignant Glioma
NCT04943718 ·Status: UNKNOWN ·Phase: PHASE1
-
Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma
NCT01290692 ·Status: COMPLETED ·Phase: PHASE2
-
CT-322 in Combination With Radiation Therapy and Temozolomide to Treat Newly Diagnosed Glioblastoma Multiforme
NCT00768911 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma
NCT05802693 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Evaluating the Safety and Efficacy of BioTTT001 in Patients With Recurrent/Progressive High-grade Glioma.
NCT06763965 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1/PHASE2
-
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
NCT02287428 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
NCT04977375 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas
NCT02520882 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine
NCT02722512 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy Study to Treat Recurrent Grade 4 Malignant Brain Tumors
NCT00071539 ·Status: COMPLETED ·Phase: PHASE2
-
Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery
NCT04968366 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccination With Lethally Irradiated Glioma Cells Mixed With GM-K562 Cells in Patients Undergoing Craniotomy For Recurrent Tumor
NCT00694330 ·Status: COMPLETED ·Phase: PHASE1