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Exercise and Repetitive Diving

NCT02118207 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2014-04-21

No results posted yet for this study

Summary

SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives.

16 divers in 2 groups each completed 6 dives. One group completed 3 control dives followed by 5 days rest then 3 dives preceded by exercise. The other group completed the opposite protocol. Flow-mediated dilation (FMD) data and blood for MP analysis was collected before and after each dive. VGE were monitored via transthoracic echocardiography 30, 60, and 90 min after surfacing. Exercise before diving consisted of 60 min running outdoors including 8x4 min intervals at 90% VO2max effort.

Conditions

  • Decompression Sickness
  • Endothelial Dysfunction
  • Neutrophil Activation
  • Venous Gas Emboli

Interventions

OTHER

Aerobic running exercise

60 min of aerobic intervals completed prior to SCUBA diving

Sponsors & Collaborators

  • University of Maryland

    collaborator OTHER

  • University Hospital of Split

    lead OTHER

Principal Investigators

  • Zeljko Dujic, MD, PhD · University of Split, School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2013-11-30
Completion
2014-01-31

Countries

  • United States
  • Croatia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02118207 on ClinicalTrials.gov