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The Role of the Endocannabinoid System in Sweet Taste Intensity and Liking

NCT02112292 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2017-05-23

No results posted yet for this study

Summary

The endocannabinoid (eCB) system, a neurochemical signalling system consisting of CB-receptors and their endogenous ligands, has been found to be involved in food intake of sweet and palatable foods. Activation of the eCB system increases food intake and vice versa. The mechanism behind this effect is still unknown and the current study aims at clarifying why sweet food intake increases. It is hypothesized that sweet taste intensity increases and that sweet taste is experienced as more pleasant.

Conditions

  • Sensory Science

Interventions

DRUG

tetrahydrocannabinol

DRUG

cannabidiol

DRUG

Placebo

Sponsors & Collaborators

  • Wageningen University

    lead OTHER

Principal Investigators

  • Suzanne EM de Bruijn, MSc · Wageningen University

  • Gerry Jager, Dr. · Wageningen University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2015-04-16
Completion
2015-04-16

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02112292 on ClinicalTrials.gov