Study of TENS in Reducing Symptoms of Peripheral Neuropathy Induced by Chemotherapy

Summary

This study aims to investigate the effects of Transcutaneous Electrical Nerve Stimulation (TENS) in reducing the symptoms of pain and numbness and improve the daily lives of cancer patients who have Chemotherapy-induced peripheral neuropathy (CIPN).

Conditions

• Peripheral Neuropathy
• Pain
• Paresthesia
• Neuritis

Interventions

DEVICE

active TENS

Experimental Group (EG) who will receive the application of active TENS. The participants of these group will receive TENS within the following parameters: VF mode TENS with a variable frequency between 7 Hz and 65 Hz. It has a pulse width of 200 µs, this is the highest tolerable intensity while still remaining comfortable for the patient. It has an application time of 60 minutes with the highest tolerable intensity, while still remaining comfortable for the patient.

DEVICE

placebo TENS

who will be administering the placebo TENS.The participants of these group will receive TENS within the following parameters: VF mode TENS with a variable frequency between 7 Hz and 65 Hz. It has a pulse width of 200 µs, this is the highest tolerable intensity while still remaining comfortable for the patient. It has an application time of 60 minutes The TENS-placebo will be applied where no current will be emitted. Patients in the placebo group will only feel the tingling for 45 seconds and after this period the device will not emit impulses, but it will work for 1 hour.

Sponsors & Collaborators

• Instituto Nacional de Cancer, Brazil

  collaborator OTHER_GOV

• Instituto do Cancer do Estado de São Paulo

  collaborator OTHER

• Hospital de Câncer de Barretos

  collaborator OTHER

• Centro de Estudos e Pesquisas Oncológicas (CEPO)

  collaborator UNKNOWN

• Centro de Oncologia do Hospital Universitário São Francisco

  collaborator UNKNOWN

• University of Sao Paulo General Hospital

  lead OTHER

Principal Investigators

• Tania Tonezzer, B.S · Post-Graduation Student of Rehabilitation Science Program from Department of Speech Therapy, Physical Therapy and Occupational Therapy, São Paulo University, São Paulo, Brazil.

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-06-30

Primary Completion

2015-12-31

Completion

2017-12-31

Countries

• Brazil

Study Locations