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MRI Optimization Study in Stage III NSCLC

NCT02076282 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2015-02-03

No results posted yet for this study

Summary

Radiation therapy uses radiation to treat lung tumors and metastases in the mediastinum. In order to irradiate as precise as possible, and in order to evaluate the effect of radiation treatment, it is important to depict the lung tumor and the lymph node metastases as accurate as possible. Currently, radiation oncologists use PET-CT for this purpose. However, PET-CT does have its drawbacks, and partly because of this, large volumes are irradiated in current treatment.

The investigators believe that MRI can be used to improve depiction of the tumor and lymph nodes and of their motion. However, there is currently no MRI protocol available which is aimed at improving radiotherapy.

In this study, the investigators want to select the optimal MRI settings for depiction of the lung tumor, the lymph node metastases and their movement.

The investigators plan to do this by first examining 10 healthy volunteers, followed by 20 patients with non-small cell lung cancer.

Conditions

  • Stage III Non-small Cell Lung Cancer

Interventions

OTHER

1 MRI scan

For healthy volunteers: 1 MRI scan without contrast For patients: 1 MRI scan with contrast

Sponsors & Collaborators

  • UMC Utrecht

    lead OTHER

Principal Investigators

  • Marco van Vulpen, MD, PhD · UMC Utrecht

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2015-11-30
Completion
2015-11-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02076282 on ClinicalTrials.gov